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Volume of Plasma Cleared of Drug given Rate at which Drug is Removed Calculator

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✖Elimination Rate Constant is the rate at which a drug is removed from the body.ⓘ Elimination Rate Constant [k_e]			+10% -10%
✖The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.ⓘ Volume of Distribution [V_d]			+10% -10%

✖The Volume of Plasma Cleared is defined as the amount of plasma cleared of the drug per unit of time.ⓘ Volume of Plasma Cleared of Drug given Rate at which Drug is Removed [CL]

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Volume of Plasma Cleared of Drug given Rate at which Drug is Removed Solution

STEP 0: Pre-Calculation Summary

Formula Used

Volume of Plasma Cleared = Elimination Rate Constant*Volume of Distribution
CL = k_e*V_d
This formula uses 3 Variables

Variables Used

Volume of Plasma Cleared - (Measured in Cubic Meter per Second) - The Volume of Plasma Cleared is defined as the amount of plasma cleared of the drug per unit of time.
Elimination Rate Constant - (Measured in 1 Per Second) - Elimination Rate Constant is the rate at which a drug is removed from the body.
Volume of Distribution - (Measured in Cubic Meter) - The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.

STEP 1: Convert Input(s) to Base Unit

Elimination Rate Constant: 0.058 1 Per Hour --> 1.61111111111111E-05 1 Per Second (Check conversion here)
Volume of Distribution: 9 Liter --> 0.009 Cubic Meter (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

CL = k_e*V_d --> 1.61111111111111E-05*0.009

Evaluating ... ...

CL = 1.45E-07

STEP 3: Convert Result to Output's Unit

1.45E-07 Cubic Meter per Second -->0.000145 Liter per Second (Check conversion here)

FINAL ANSWER

0.000145 Liter per Second <-- Volume of Plasma Cleared

(Calculation completed in 00.004 seconds)

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< Volume of plasma cleared Calculators

Volume of Plasma Cleared given Elimination Half Life

LaTeX Go Volume of Plasma Cleared = (ln(2)*Volume of Distribution)/Elimination Half Life

Volume of Plasma Cleared of Drug given Rate at which Drug is Removed

LaTeX Go Volume of Plasma Cleared = Elimination Rate Constant*Volume of Distribution

Volume of Plasma Cleared given Rate of Infusion

LaTeX Go Volume of Plasma Cleared = Rate of Infusion/Concentration of Drug

Volume of Plasma Cleared given Area under Curve

LaTeX Go Volume of Plasma Cleared = Dose/Area Under Curve

Volume of Plasma Cleared of Drug given Rate at which Drug is Removed Formula

LaTeX Go

Volume of Plasma Cleared = Elimination Rate Constant*Volume of Distribution
CL = k_e*V_d

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Volume of Plasma Cleared of Drug given Rate at which Drug is Removed?

Volume of Plasma Cleared of Drug given Rate at which Drug is Removed calculator uses Volume of Plasma Cleared = Elimination Rate Constant*Volume of Distribution to calculate the Volume of Plasma Cleared, The Volume of plasma cleared of drug given rate at which drug is removed formula is defined as the product of the rate at which a drug is removed from the body to the apparent volume in which a drug is distributed. Volume of Plasma Cleared is denoted by CL symbol.

How to calculate Volume of Plasma Cleared of Drug given Rate at which Drug is Removed using this online calculator? To use this online calculator for Volume of Plasma Cleared of Drug given Rate at which Drug is Removed, enter Elimination Rate Constant (k_e) & Volume of Distribution (V_d) and hit the calculate button. Here is how the Volume of Plasma Cleared of Drug given Rate at which Drug is Removed calculation can be explained with given input values -> 0.145 = 1.61111111111111E-05*0.009.

FAQ

What is Volume of Plasma Cleared of Drug given Rate at which Drug is Removed?

The Volume of plasma cleared of drug given rate at which drug is removed formula is defined as the product of the rate at which a drug is removed from the body to the apparent volume in which a drug is distributed and is represented as CL = k_e*V_d or Volume of Plasma Cleared = Elimination Rate Constant*Volume of Distribution. Elimination Rate Constant is the rate at which a drug is removed from the body & The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.

How to calculate Volume of Plasma Cleared of Drug given Rate at which Drug is Removed?

The Volume of plasma cleared of drug given rate at which drug is removed formula is defined as the product of the rate at which a drug is removed from the body to the apparent volume in which a drug is distributed is calculated using Volume of Plasma Cleared = Elimination Rate Constant*Volume of Distribution. To calculate Volume of Plasma Cleared of Drug given Rate at which Drug is Removed, you need Elimination Rate Constant (k_e) & Volume of Distribution (V_d). With our tool, you need to enter the respective value for Elimination Rate Constant & Volume of Distribution and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Volume of Plasma Cleared?

In this formula, Volume of Plasma Cleared uses Elimination Rate Constant & Volume of Distribution. We can use 3 other way(s) to calculate the same, which is/are as follows -

Volume of Plasma Cleared = (ln(2)*Volume of Distribution)/Elimination Half Life
Volume of Plasma Cleared = Rate of Infusion/Concentration of Drug
Volume of Plasma Cleared = Dose/Area Under Curve

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