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Volume of Plasma Cleared given Rate of Infusion Calculator

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✖The Rate of Infusion is defined as the rate required to balance elimination.ⓘ Rate of Infusion [k_in]			+10% -10%
✖Concentration of Drug is the amount of the drug in a given volume of plasma.ⓘ Concentration of Drug [C_ss]			+10% -10%

✖The Volume of Plasma Cleared is defined as the amount of plasma cleared of the drug per unit of time.ⓘ Volume of Plasma Cleared given Rate of Infusion [CL]

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Volume of Plasma Cleared given Rate of Infusion Solution

STEP 0: Pre-Calculation Summary

Formula Used

Volume of Plasma Cleared = Rate of Infusion/Concentration of Drug
CL = k_in/C_ss
This formula uses 3 Variables

Variables Used

Volume of Plasma Cleared - (Measured in Cubic Meter per Second) - The Volume of Plasma Cleared is defined as the amount of plasma cleared of the drug per unit of time.
Rate of Infusion - (Measured in Mole per Second) - The Rate of Infusion is defined as the rate required to balance elimination.
Concentration of Drug - (Measured in Mole per Cubic Meter) - Concentration of Drug is the amount of the drug in a given volume of plasma.

STEP 1: Convert Input(s) to Base Unit

Rate of Infusion: 55 Mole per Second --> 55 Mole per Second No Conversion Required
Concentration of Drug: 83.3 Mole per Liter --> 83300 Mole per Cubic Meter (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

CL = k_in/C_ss --> 55/83300

Evaluating ... ...

CL = 0.000660264105642257

STEP 3: Convert Result to Output's Unit

0.000660264105642257 Cubic Meter per Second -->0.660264105642257 Liter per Second (Check conversion here)

FINAL ANSWER

0.660264105642257 ≈ 0.660264 Liter per Second <-- Volume of Plasma Cleared

(Calculation completed in 00.007 seconds)

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LaTeX Go Volume of Plasma Cleared = (ln(2)*Volume of Distribution)/Elimination Half Life

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LaTeX Go Volume of Plasma Cleared = Elimination Rate Constant*Volume of Distribution

Volume of Plasma Cleared given Rate of Infusion

LaTeX Go Volume of Plasma Cleared = Rate of Infusion/Concentration of Drug

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LaTeX Go Volume of Plasma Cleared = Dose/Area Under Curve

Volume of Plasma Cleared given Rate of Infusion Formula

LaTeX Go

Volume of Plasma Cleared = Rate of Infusion/Concentration of Drug
CL = k_in/C_ss

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Volume of Plasma Cleared given Rate of Infusion?

Volume of Plasma Cleared given Rate of Infusion calculator uses Volume of Plasma Cleared = Rate of Infusion/Concentration of Drug to calculate the Volume of Plasma Cleared, The Volume of plasma cleared given rate of infusion formula is defined as the ratio of the rate of infusion required to balance elimination to the amount of drug in a given volume of plasma. Volume of Plasma Cleared is denoted by CL symbol.

How to calculate Volume of Plasma Cleared given Rate of Infusion using this online calculator? To use this online calculator for Volume of Plasma Cleared given Rate of Infusion, enter Rate of Infusion (k_in) & Concentration of Drug (C_ss) and hit the calculate button. Here is how the Volume of Plasma Cleared given Rate of Infusion calculation can be explained with given input values -> 660.2641 = 55/83300.

FAQ

What is Volume of Plasma Cleared given Rate of Infusion?

The Volume of plasma cleared given rate of infusion formula is defined as the ratio of the rate of infusion required to balance elimination to the amount of drug in a given volume of plasma and is represented as CL = k_in/C_ss or Volume of Plasma Cleared = Rate of Infusion/Concentration of Drug. The Rate of Infusion is defined as the rate required to balance elimination & Concentration of Drug is the amount of the drug in a given volume of plasma.

How to calculate Volume of Plasma Cleared given Rate of Infusion?

The Volume of plasma cleared given rate of infusion formula is defined as the ratio of the rate of infusion required to balance elimination to the amount of drug in a given volume of plasma is calculated using Volume of Plasma Cleared = Rate of Infusion/Concentration of Drug. To calculate Volume of Plasma Cleared given Rate of Infusion, you need Rate of Infusion (k_in) & Concentration of Drug (C_ss). With our tool, you need to enter the respective value for Rate of Infusion & Concentration of Drug and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Volume of Plasma Cleared?

In this formula, Volume of Plasma Cleared uses Rate of Infusion & Concentration of Drug. We can use 3 other way(s) to calculate the same, which is/are as follows -

Volume of Plasma Cleared = Elimination Rate Constant*Volume of Distribution
Volume of Plasma Cleared = (ln(2)*Volume of Distribution)/Elimination Half Life
Volume of Plasma Cleared = Dose/Area Under Curve

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