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Secretion Rate of Drug Calculator

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✖Renal Clearance is a measure of kidney transport in units of volume of plasma per unit time.ⓘ Renal Clearance [CL_r]			+10% -10%
✖Plasma Concentration is the concentration of the drug after administration and before the next dose is administered.ⓘ Plasma Concentration [C_p]			+10% -10%
✖Filtration Rate is the estimates of how much blood passes through the glomeruli each minute.ⓘ Filtration Rate [F_rate]			+10% -10%
✖Reabsorption Rate of Drug is the measure of movement of drug and solutes from the tubule back into the plasma.ⓘ Reabsorption Rate of Drug [R_rate]			+10% -10%

✖Secretion Rate of Drug is the measure of the removal of drugs from the body, either as a metabolite or unchanged drug.ⓘ Secretion Rate of Drug [S_rate]

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Secretion Rate of Drug Solution

STEP 0: Pre-Calculation Summary

Formula Used

Secretion Rate of Drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug)
S_rate = (CL_r*C_p)-(F_rate)+(R_rate)
This formula uses 5 Variables

Variables Used

Secretion Rate of Drug - (Measured in Cubic meter per second) - Secretion Rate of Drug is the measure of the removal of drugs from the body, either as a metabolite or unchanged drug.
Renal Clearance - (Measured in Cubic Meter per Second) - Renal Clearance is a measure of kidney transport in units of volume of plasma per unit time.
Plasma Concentration - (Measured in Mole per Cubic Meter) - Plasma Concentration is the concentration of the drug after administration and before the next dose is administered.
Filtration Rate - (Measured in Cubic meter per second) - Filtration Rate is the estimates of how much blood passes through the glomeruli each minute.
Reabsorption Rate of Drug - (Measured in Cubic meter per second) - Reabsorption Rate of Drug is the measure of movement of drug and solutes from the tubule back into the plasma.

STEP 1: Convert Input(s) to Base Unit

Renal Clearance: 15.6 Milliliter per Minute --> 2.6E-07 Cubic Meter per Second (Check conversion here)
Plasma Concentration: 17 Mole per Liter --> 17000 Mole per Cubic Meter (Check conversion here)
Filtration Rate: 14 Milliliter per Minute --> 2.33333333333333E-07 Cubic meter per second (Check conversion here)
Reabsorption Rate of Drug: 14.5 Milliliter per Minute --> 2.41666666666667E-07 Cubic meter per second (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

S_rate = (CL_r*C_p)-(F_rate)+(R_rate) --> (2.6E-07*17000)-(2.33333333333333E-07)+(2.41666666666667E-07)

Evaluating ... ...

S_rate = 0.00442000833333333

STEP 3: Convert Result to Output's Unit

0.00442000833333333 Cubic meter per second -->265200.5 Milliliter per Minute (Check conversion here)

FINAL ANSWER

265200.5 Milliliter per Minute <-- Secretion Rate of Drug

(Calculation completed in 00.004 seconds)

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National University of Judicial Science (NUJS), Kolkata

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< Drug Content Calculators

Rate of Infusion of Drug

LaTeX Go Rate of Infusion = Volume of Plasma Cleared*Concentration of Drug

Absorption Half-Life of Drug

LaTeX Go Absorption Half Life = ln(2)/Absorption Rate Constant

Drug Rate Entering Body

LaTeX Go Absorption Rate Constant = ln(2)/Absorption Half Life

Apparent Volume of Drug Distribution

LaTeX Go Volume of Distribution = Dose/Concentration of Drug

Secretion Rate of Drug Formula

LaTeX Go

Secretion Rate of Drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug)
S_rate = (CL_r*C_p)-(F_rate)+(R_rate)

What is Pharmacokinetics ?

Pharmacokinetics is currently defined as the study of the time course of drug absorption, distribution, metabolism, and excretion. Clinical pharmacokinetics is the application of pharmacokinetic principles to the safe and effective therapeutic management of drugs in an individual patient

How to Calculate Secretion Rate of Drug?

Secretion Rate of Drug calculator uses Secretion Rate of Drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug) to calculate the Secretion Rate of Drug, The Secretion Rate of Drug formula is defined as excretion of some substance such as hydrogen ions, creatinine, and drugs which will be removed from the blood through the peritubular capillary network into the collecting duct. Secretion Rate of Drug is denoted by S_rate symbol.

How to calculate Secretion Rate of Drug using this online calculator? To use this online calculator for Secretion Rate of Drug, enter Renal Clearance (CL_r), Plasma Concentration (C_p), Filtration Rate (F_rate) & Reabsorption Rate of Drug (R_rate) and hit the calculate button. Here is how the Secretion Rate of Drug calculation can be explained with given input values -> 1.6E+13 = (2.6E-07*17000)-(2.33333333333333E-07)+(2.41666666666667E-07).

FAQ

What is Secretion Rate of Drug?

The Secretion Rate of Drug formula is defined as excretion of some substance such as hydrogen ions, creatinine, and drugs which will be removed from the blood through the peritubular capillary network into the collecting duct and is represented as S_rate = (CL_r*C_p)-(F_rate)+(R_rate) or Secretion Rate of Drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug). Renal Clearance is a measure of kidney transport in units of volume of plasma per unit time, Plasma Concentration is the concentration of the drug after administration and before the next dose is administered, Filtration Rate is the estimates of how much blood passes through the glomeruli each minute & Reabsorption Rate of Drug is the measure of movement of drug and solutes from the tubule back into the plasma.

How to calculate Secretion Rate of Drug?

The Secretion Rate of Drug formula is defined as excretion of some substance such as hydrogen ions, creatinine, and drugs which will be removed from the blood through the peritubular capillary network into the collecting duct is calculated using Secretion Rate of Drug = (Renal Clearance*Plasma Concentration)-(Filtration Rate)+(Reabsorption Rate of Drug). To calculate Secretion Rate of Drug, you need Renal Clearance (CL_r), Plasma Concentration (C_p), Filtration Rate (F_rate) & Reabsorption Rate of Drug (R_rate). With our tool, you need to enter the respective value for Renal Clearance, Plasma Concentration, Filtration Rate & Reabsorption Rate of Drug and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

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