Reverse Rate Constant given Forward and Catalytic Rate Constants Calculator

✖The Forward Rate Constant is defined as the rate constant for the forward occurring reaction.ⓘ Forward Rate Constant [k_f]			+10% -10%
✖The Catalyst Concentration is the number of moles of catalyst present in the per liter of solution.ⓘ Catalyst Concentration [E]			+10% -10%
✖The Substrate Concentration is the number of moles of substrate per liter solution.ⓘ Substrate Concentration [S]			+10% -10%
✖The Enzyme Substrate Complex Concentration is defined as the concentration of intermediate formed from the reaction of enzyme and substrate.ⓘ Enzyme Substrate Complex Concentration [ES]			+10% -10%
✖The Catalytic Rate Constant is defined as the rate constant for conversion of the enzyme-substrate complex to enzyme and product.ⓘ Catalytic Rate Constant [k_cat]			+10% -10%

✖The Reverse Rate Constant is defined as the rate constant for the backward reaction.ⓘ Reverse Rate Constant given Forward and Catalytic Rate Constants [k_r]

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Reverse Rate Constant given Forward and Catalytic Rate Constants Solution

STEP 0: Pre-Calculation Summary

Formula Used

Reverse Rate Constant = ((Forward Rate Constant*Catalyst Concentration*Substrate Concentration)/Enzyme Substrate Complex Concentration)-Catalytic Rate Constant
k_r = ((k_f*E*S)/ES)-k_cat
This formula uses 6 Variables

Variables Used

Reverse Rate Constant - (Measured in Mole per Cubic Meter Second) - The Reverse Rate Constant is defined as the rate constant for the backward reaction.
Forward Rate Constant - (Measured in 1 Per Second) - The Forward Rate Constant is defined as the rate constant for the forward occurring reaction.
Catalyst Concentration - (Measured in Mole per Cubic Meter) - The Catalyst Concentration is the number of moles of catalyst present in the per liter of solution.
Substrate Concentration - (Measured in Mole per Cubic Meter) - The Substrate Concentration is the number of moles of substrate per liter solution.
Enzyme Substrate Complex Concentration - (Measured in Mole per Cubic Meter) - The Enzyme Substrate Complex Concentration is defined as the concentration of intermediate formed from the reaction of enzyme and substrate.
Catalytic Rate Constant - (Measured in 1 Per Second) - The Catalytic Rate Constant is defined as the rate constant for conversion of the enzyme-substrate complex to enzyme and product.

STEP 1: Convert Input(s) to Base Unit

Forward Rate Constant: 6.9 1 Per Second --> 6.9 1 Per Second No Conversion Required
Catalyst Concentration: 25 Mole per Liter --> 25000 Mole per Cubic Meter (Check conversion here)
Substrate Concentration: 1.5 Mole per Liter --> 1500 Mole per Cubic Meter (Check conversion here)
Enzyme Substrate Complex Concentration: 10 Mole per Liter --> 10000 Mole per Cubic Meter (Check conversion here)
Catalytic Rate Constant: 0.65 1 Per Second --> 0.65 1 Per Second No Conversion Required

STEP 2: Evaluate Formula

Substituting Input Values in Formula

k_r = ((k_f*E*S)/ES)-k_cat --> ((6.9*25000*1500)/10000)-0.65

Evaluating ... ...

k_r = 25874.35

STEP 3: Convert Result to Output's Unit

25874.35 Mole per Cubic Meter Second -->25.87435 Mole per Liter Second (Check conversion here)

FINAL ANSWER

25.87435 Mole per Liter Second <-- Reverse Rate Constant

(Calculation completed in 00.020 seconds)

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< Rate Constants of Enzymatic Reaction Calculators

Forward Rate Constant in Enzymatic Reaction mechanism

LaTeX Go Forward Rate Constant = (Reverse Rate Constant*Enzyme Substrate Complex Concentration)/(Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))

Reverse Rate Constant in Enzymatic Reaction Mechanism

LaTeX Go Reverse Rate Constant = (Forward Rate Constant*Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))/Enzyme Substrate Complex Concentration

Catalytic Rate Constant at Low Substrate Concentration

LaTeX Go Catalytic Rate Constant = (Initial Reaction Rate*Michaelis Constant)/(Initial Enzyme Concentration*Substrate Concentration)

Dissociation Rate Constant in Enzymatic Reaction Mechanism

LaTeX Go Dissociation Rate Constant = Reverse Rate Constant/Forward Rate Constant

Reverse Rate Constant given Forward and Catalytic Rate Constants Formula

LaTeX Go

Reverse Rate Constant = ((Forward Rate Constant*Catalyst Concentration*Substrate Concentration)/Enzyme Substrate Complex Concentration)-Catalytic Rate Constant
k_r = ((k_f*E*S)/ES)-k_cat

What is Michaelis–Menten kinetics model?

In biochemistry, Michaelis–Menten kinetics is one of the best-known models of enzyme kinetics. Biochemical reactions involving a single substrate are often assumed to follow Michaelis–Menten kinetics, without regard to the model's underlying assumptions. The model takes the form of an equation describing the rate of enzymatic reactions, by relating the reaction rate of formation of product to the concentration of a substrate.

How to Calculate Reverse Rate Constant given Forward and Catalytic Rate Constants?

Reverse Rate Constant given Forward and Catalytic Rate Constants calculator uses Reverse Rate Constant = ((Forward Rate Constant*Catalyst Concentration*Substrate Concentration)/Enzyme Substrate Complex Concentration)-Catalytic Rate Constant to calculate the Reverse Rate Constant, The Reverse rate constant given forward and catalytic rate constants formula is defined as the relation with enzymatic catalyst and substrate concentration with an enzyme-substrate complex concentration in an enzymatic reaction mechanism. Reverse Rate Constant is denoted by k_r symbol.

How to calculate Reverse Rate Constant given Forward and Catalytic Rate Constants using this online calculator? To use this online calculator for Reverse Rate Constant given Forward and Catalytic Rate Constants, enter Forward Rate Constant (k_f), Catalyst Concentration (E), Substrate Concentration (S), Enzyme Substrate Complex Concentration (ES) & Catalytic Rate Constant (k_cat) and hit the calculate button. Here is how the Reverse Rate Constant given Forward and Catalytic Rate Constants calculation can be explained with given input values -> 0.025874 = ((6.9*25000*1500)/10000)-0.65.

FAQ

What is Reverse Rate Constant given Forward and Catalytic Rate Constants?

The Reverse rate constant given forward and catalytic rate constants formula is defined as the relation with enzymatic catalyst and substrate concentration with an enzyme-substrate complex concentration in an enzymatic reaction mechanism and is represented as k_r = ((k_f*E*S)/ES)-k_cat or Reverse Rate Constant = ((Forward Rate Constant*Catalyst Concentration*Substrate Concentration)/Enzyme Substrate Complex Concentration)-Catalytic Rate Constant. The Forward Rate Constant is defined as the rate constant for the forward occurring reaction, The Catalyst Concentration is the number of moles of catalyst present in the per liter of solution, The Substrate Concentration is the number of moles of substrate per liter solution, The Enzyme Substrate Complex Concentration is defined as the concentration of intermediate formed from the reaction of enzyme and substrate & The Catalytic Rate Constant is defined as the rate constant for conversion of the enzyme-substrate complex to enzyme and product.

How to calculate Reverse Rate Constant given Forward and Catalytic Rate Constants?

The Reverse rate constant given forward and catalytic rate constants formula is defined as the relation with enzymatic catalyst and substrate concentration with an enzyme-substrate complex concentration in an enzymatic reaction mechanism is calculated using Reverse Rate Constant = ((Forward Rate Constant*Catalyst Concentration*Substrate Concentration)/Enzyme Substrate Complex Concentration)-Catalytic Rate Constant. To calculate Reverse Rate Constant given Forward and Catalytic Rate Constants, you need Forward Rate Constant (k_f), Catalyst Concentration (E), Substrate Concentration (S), Enzyme Substrate Complex Concentration (ES) & Catalytic Rate Constant (k_cat). With our tool, you need to enter the respective value for Forward Rate Constant, Catalyst Concentration, Substrate Concentration, Enzyme Substrate Complex Concentration & Catalytic Rate Constant and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Reverse Rate Constant?

In this formula, Reverse Rate Constant uses Forward Rate Constant, Catalyst Concentration, Substrate Concentration, Enzyme Substrate Complex Concentration & Catalytic Rate Constant. We can use 3 other way(s) to calculate the same, which is/are as follows -

Reverse Rate Constant = (Forward Rate Constant*Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))/Enzyme Substrate Complex Concentration
Reverse Rate Constant = (Dissociation Rate Constant*Forward Rate Constant)
Reverse Rate Constant = (Michaelis Constant*Forward Rate Constant)-Catalytic Rate Constant

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