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Renal Clearance using Rate of Reabsorption Calculator

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✖Filtration Rate is the estimates of how much blood passes through the glomeruli each minute.ⓘ Filtration Rate [F_rate]			+10% -10%
✖Secretion Rate of Drug is the measure of the removal of drugs from the body, either as a metabolite or unchanged drug.ⓘ Secretion Rate of Drug [S_rate]			+10% -10%
✖Reabsorption Rate of Drug is the measure of movement of drug and solutes from the tubule back into the plasma.ⓘ Reabsorption Rate of Drug [R_rate]			+10% -10%
✖Plasma Concentration is the concentration of the drug after administration and before the next dose is administered.ⓘ Plasma Concentration [C_p]			+10% -10%

✖Renal Clearance is a measure of kidney transport in units of volume of plasma per unit time.ⓘ Renal Clearance using Rate of Reabsorption [CL_r]

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Renal Clearance using Rate of Reabsorption Solution

STEP 0: Pre-Calculation Summary

Formula Used

Renal Clearance = Filtration Rate+(Secretion Rate of Drug-Reabsorption Rate of Drug)/Plasma Concentration
CL_r = F_rate+(S_rate-R_rate)/C_p
This formula uses 5 Variables

Variables Used

Renal Clearance - (Measured in Cubic Meter per Second) - Renal Clearance is a measure of kidney transport in units of volume of plasma per unit time.
Filtration Rate - (Measured in Cubic meter per second) - Filtration Rate is the estimates of how much blood passes through the glomeruli each minute.
Secretion Rate of Drug - (Measured in Cubic meter per second) - Secretion Rate of Drug is the measure of the removal of drugs from the body, either as a metabolite or unchanged drug.
Reabsorption Rate of Drug - (Measured in Cubic meter per second) - Reabsorption Rate of Drug is the measure of movement of drug and solutes from the tubule back into the plasma.
Plasma Concentration - (Measured in Mole per Cubic Meter) - Plasma Concentration is the concentration of the drug after administration and before the next dose is administered.

STEP 1: Convert Input(s) to Base Unit

Filtration Rate: 14 Milliliter per Minute --> 2.33333333333333E-07 Cubic meter per second (Check conversion here)
Secretion Rate of Drug: 10.4 Milliliter per Minute --> 1.73333333333333E-07 Cubic meter per second (Check conversion here)
Reabsorption Rate of Drug: 14.5 Milliliter per Minute --> 2.41666666666667E-07 Cubic meter per second (Check conversion here)
Plasma Concentration: 17 Mole per Liter --> 17000 Mole per Cubic Meter (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

CL_r = F_rate+(S_rate-R_rate)/C_p --> 2.33333333333333E-07+(1.73333333333333E-07-2.41666666666667E-07)/17000

Evaluating ... ...

CL_r = 2.3332931372549E-07

STEP 3: Convert Result to Output's Unit

2.3332931372549E-07 Cubic Meter per Second -->13.9997588235294 Milliliter per Minute (Check conversion here)

FINAL ANSWER

13.9997588235294 ≈ 13.99976 Milliliter per Minute <-- Renal Clearance

(Calculation completed in 00.007 seconds)

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Renal Clearance using Rate of Reabsorption Formula

LaTeX Go

Renal Clearance = Filtration Rate+(Secretion Rate of Drug-Reabsorption Rate of Drug)/Plasma Concentration
CL_r = F_rate+(S_rate-R_rate)/C_p

What is Pharmacokinetics ?

Pharmacokinetics is currently defined as the study of the time course of drug absorption, distribution, metabolism, and excretion. Clinical pharmacokinetics is the application of pharmacokinetic principles to the safe and effective therapeutic management of drugs in an individual patient.

How to Calculate Renal Clearance using Rate of Reabsorption?

Renal Clearance using Rate of Reabsorption calculator uses Renal Clearance = Filtration Rate+(Secretion Rate of Drug-Reabsorption Rate of Drug)/Plasma Concentration to calculate the Renal Clearance, The Renal Clearance using Rate of reabsorption formula is defined as measurement of the volume of plasma that is removed of a specific substance over a period of time without a negligible reabsorption of drug. Renal Clearance is denoted by CL_r symbol.

How to calculate Renal Clearance using Rate of Reabsorption using this online calculator? To use this online calculator for Renal Clearance using Rate of Reabsorption, enter Filtration Rate (F_rate), Secretion Rate of Drug (S_rate), Reabsorption Rate of Drug (R_rate) & Plasma Concentration (C_p) and hit the calculate button. Here is how the Renal Clearance using Rate of Reabsorption calculation can be explained with given input values -> 8.4E+8 = 2.33333333333333E-07+(1.73333333333333E-07-2.41666666666667E-07)/17000.

FAQ

What is Renal Clearance using Rate of Reabsorption?

The Renal Clearance using Rate of reabsorption formula is defined as measurement of the volume of plasma that is removed of a specific substance over a period of time without a negligible reabsorption of drug and is represented as CL_r = F_rate+(S_rate-R_rate)/C_p or Renal Clearance = Filtration Rate+(Secretion Rate of Drug-Reabsorption Rate of Drug)/Plasma Concentration. Filtration Rate is the estimates of how much blood passes through the glomeruli each minute, Secretion Rate of Drug is the measure of the removal of drugs from the body, either as a metabolite or unchanged drug, Reabsorption Rate of Drug is the measure of movement of drug and solutes from the tubule back into the plasma & Plasma Concentration is the concentration of the drug after administration and before the next dose is administered.

How to calculate Renal Clearance using Rate of Reabsorption?

The Renal Clearance using Rate of reabsorption formula is defined as measurement of the volume of plasma that is removed of a specific substance over a period of time without a negligible reabsorption of drug is calculated using Renal Clearance = Filtration Rate+(Secretion Rate of Drug-Reabsorption Rate of Drug)/Plasma Concentration. To calculate Renal Clearance using Rate of Reabsorption, you need Filtration Rate (F_rate), Secretion Rate of Drug (S_rate), Reabsorption Rate of Drug (R_rate) & Plasma Concentration (C_p). With our tool, you need to enter the respective value for Filtration Rate, Secretion Rate of Drug, Reabsorption Rate of Drug & Plasma Concentration and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

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