Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration Calculator

✖The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.ⓘ Initial Reaction Rate [V₀]			+10% -10%
✖The Enzyme Substrate Complex Concentration is defined as the concentration of intermediate formed from the reaction of enzyme and substrate.ⓘ Enzyme Substrate Complex Concentration [ES]			+10% -10%

✖The Final Rate Constant is the rate constant when the enzyme-substrate complex on reaction with inhibitor is converted into the enzyme catalyst and product.ⓘ Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration [k₂]

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Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration Solution

STEP 0: Pre-Calculation Summary

Formula Used

Final Rate Constant = Initial Reaction Rate/Enzyme Substrate Complex Concentration
k₂ = V₀/ES
This formula uses 3 Variables

Variables Used

Final Rate Constant - (Measured in 1 Per Second) - The Final Rate Constant is the rate constant when the enzyme-substrate complex on reaction with inhibitor is converted into the enzyme catalyst and product.
Initial Reaction Rate - (Measured in Mole per Cubic Meter Second) - The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.
Enzyme Substrate Complex Concentration - (Measured in Mole per Cubic Meter) - The Enzyme Substrate Complex Concentration is defined as the concentration of intermediate formed from the reaction of enzyme and substrate.

STEP 1: Convert Input(s) to Base Unit

Initial Reaction Rate: 0.45 Mole per Liter Second --> 450 Mole per Cubic Meter Second (Check conversion here)
Enzyme Substrate Complex Concentration: 10 Mole per Liter --> 10000 Mole per Cubic Meter (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

k₂ = V₀/ES --> 450/10000

Evaluating ... ...

k₂ = 0.045

STEP 3: Convert Result to Output's Unit

0.045 1 Per Second --> No Conversion Required

FINAL ANSWER

0.045 1 Per Second <-- Final Rate Constant

(Calculation completed in 00.004 seconds)

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< Rate Constants of Enzymatic Reaction Calculators

Forward Rate Constant in Enzymatic Reaction mechanism

LaTeX Go Forward Rate Constant = (Reverse Rate Constant*Enzyme Substrate Complex Concentration)/(Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))

Reverse Rate Constant in Enzymatic Reaction Mechanism

LaTeX Go Reverse Rate Constant = (Forward Rate Constant*Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))/Enzyme Substrate Complex Concentration

Catalytic Rate Constant at Low Substrate Concentration

LaTeX Go Catalytic Rate Constant = (Initial Reaction Rate*Michaelis Constant)/(Initial Enzyme Concentration*Substrate Concentration)

Dissociation Rate Constant in Enzymatic Reaction Mechanism

LaTeX Go Dissociation Rate Constant = Reverse Rate Constant/Forward Rate Constant

Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration Formula

LaTeX Go

Final Rate Constant = Initial Reaction Rate/Enzyme Substrate Complex Concentration
k₂ = V₀/ES

What is competitive Inhibition?

In competitive inhibition, the substrate and inhibitor cannot bind to the enzyme at the same time, as shown in the figure on the right. This usually results from the inhibitor having an affinity for the active site of an enzyme where the substrate also binds; the substrate and inhibitor compete for access to the enzyme's active site. This type of inhibition can be overcome by sufficiently high concentrations of substrate (Vmax remains constant), i.e., by out-competing the inhibitor. However, the apparent Km will increase as it takes a higher concentration of the substrate to reach the Km point, or half the Vmax. Competitive inhibitors are often similar in structure to the real substrate.

How to Calculate Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration?

Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration calculator uses Final Rate Constant = Initial Reaction Rate/Enzyme Substrate Complex Concentration to calculate the Final Rate Constant, The Rate constant given initial rate and enzyme substrate complex concentration formula is defined as the ratio of the initial rate of the system to the concentration of enzyme-substrate complex. Final Rate Constant is denoted by k₂ symbol.

How to calculate Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration using this online calculator? To use this online calculator for Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration, enter Initial Reaction Rate (V₀) & Enzyme Substrate Complex Concentration (ES) and hit the calculate button. Here is how the Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration calculation can be explained with given input values -> 0.045 = 450/10000.

FAQ

What is Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration?

The Rate constant given initial rate and enzyme substrate complex concentration formula is defined as the ratio of the initial rate of the system to the concentration of enzyme-substrate complex and is represented as k₂ = V₀/ES or Final Rate Constant = Initial Reaction Rate/Enzyme Substrate Complex Concentration. The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place & The Enzyme Substrate Complex Concentration is defined as the concentration of intermediate formed from the reaction of enzyme and substrate.

How to calculate Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration?

The Rate constant given initial rate and enzyme substrate complex concentration formula is defined as the ratio of the initial rate of the system to the concentration of enzyme-substrate complex is calculated using Final Rate Constant = Initial Reaction Rate/Enzyme Substrate Complex Concentration. To calculate Rate Constant given Initial Rate and Enzyme Substrate Complex Concentration, you need Initial Reaction Rate (V₀) & Enzyme Substrate Complex Concentration (ES). With our tool, you need to enter the respective value for Initial Reaction Rate & Enzyme Substrate Complex Concentration and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Final Rate Constant?

In this formula, Final Rate Constant uses Initial Reaction Rate & Enzyme Substrate Complex Concentration. We can use 1 other way(s) to calculate the same, which is/are as follows -

Final Rate Constant = Maximum Rate/Initial Enzyme Concentration

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