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Previous Rate of Drug Dose given Revised Dose Calculator

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✖The Revised dose calculated based on concentration of the drug in the patient's bloodstream and the concentration of the drug that was actually measured in the patient's bloodstream (measured CPSS).ⓘ Revised Dose [RD]			+10% -10%
✖The Measured Steady State Concentration Plasma is the actual concentration of the drug that is measured in the patient's bloodstream through therapeutic drug monitoring.ⓘ Measured Steady State Concentration Plasma [M_cpss]			+10% -10%
✖The Target Steady State Plasma Concentration represents the therapeutic range or the optimal concentration that is expected to provide the desired therapeutic effect.ⓘ Target Steady State Plasma Concentration [T_cpss]			+10% -10%

✖Previous Rate of Dose Rate is the dose of the medication that the patient was previously receiving.ⓘ Previous Rate of Drug Dose given Revised Dose [PDR]

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Previous Rate of Drug Dose given Revised Dose Solution

STEP 0: Pre-Calculation Summary

Formula Used

Previous Rate of Dose = (Revised Dose*Measured Steady State Concentration Plasma)/(Target Steady State Plasma Concentration)
PDR = (RD*M_cpss)/(T_cpss)
This formula uses 4 Variables

Variables Used

Previous Rate of Dose - (Measured in Kilogram) - Previous Rate of Dose Rate is the dose of the medication that the patient was previously receiving.
Revised Dose - (Measured in Kilogram) - The Revised dose calculated based on concentration of the drug in the patient's bloodstream and the concentration of the drug that was actually measured in the patient's bloodstream (measured CPSS).
Measured Steady State Concentration Plasma - (Measured in Kilogram per Cubic Meter) - The Measured Steady State Concentration Plasma is the actual concentration of the drug that is measured in the patient's bloodstream through therapeutic drug monitoring.
Target Steady State Plasma Concentration - (Measured in Kilogram per Cubic Meter) - The Target Steady State Plasma Concentration represents the therapeutic range or the optimal concentration that is expected to provide the desired therapeutic effect.

STEP 1: Convert Input(s) to Base Unit

Revised Dose: 200 Milligram --> 0.0002 Kilogram (Check conversion here)
Measured Steady State Concentration Plasma: 5 Milligram per Liter --> 0.005 Kilogram per Cubic Meter (Check conversion here)
Target Steady State Plasma Concentration: 10 Milligram per Liter --> 0.01 Kilogram per Cubic Meter (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

PDR = (RD*M_cpss)/(T_cpss) --> (0.0002*0.005)/(0.01)

Evaluating ... ...

PDR = 0.0001

STEP 3: Convert Result to Output's Unit

0.0001 Kilogram --> No Conversion Required

FINAL ANSWER

0.0001 Kilogram <-- Previous Rate of Dose

(Calculation completed in 00.004 seconds)

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Previous Rate of Drug Dose given Revised Dose Formula

LaTeX Go

Previous Rate of Dose = (Revised Dose*Measured Steady State Concentration Plasma)/(Target Steady State Plasma Concentration)
PDR = (RD*M_cpss)/(T_cpss)

What are the characteristics of the drug suitable for therapeutic drug monitoring ?

The drug must have the following properties:

a. Narrow therapeutic index
b. Marked inter-individual pharmacokinetic variability
c. The desired therapeutic effect is difficult to monitor
d. Direct correlation between plasma concentration of drug/metabolite and pharmacological effect
e. Availability of appropriate analytical test/technique to determine drug or its metabolite level.

How to Calculate Previous Rate of Drug Dose given Revised Dose?

Previous Rate of Drug Dose given Revised Dose calculator uses Previous Rate of Dose = (Revised Dose*Measured Steady State Concentration Plasma)/(Target Steady State Plasma Concentration) to calculate the Previous Rate of Dose, The Previous Rate of Drug Dose given Revised Dose formula is defined as the ratio of the product of the revised dose and measured steady state plasma concentration to the target steady state plasma concentration. Previous Rate of Dose is denoted by PDR symbol.

How to calculate Previous Rate of Drug Dose given Revised Dose using this online calculator? To use this online calculator for Previous Rate of Drug Dose given Revised Dose, enter Revised Dose (RD), Measured Steady State Concentration Plasma (M_cpss) & Target Steady State Plasma Concentration (T_cpss) and hit the calculate button. Here is how the Previous Rate of Drug Dose given Revised Dose calculation can be explained with given input values -> 0.0001 = (0.0002*0.005)/(0.01).

FAQ

What is Previous Rate of Drug Dose given Revised Dose?

The Previous Rate of Drug Dose given Revised Dose formula is defined as the ratio of the product of the revised dose and measured steady state plasma concentration to the target steady state plasma concentration and is represented as PDR = (RD*M_cpss)/(T_cpss) or Previous Rate of Dose = (Revised Dose*Measured Steady State Concentration Plasma)/(Target Steady State Plasma Concentration). The Revised dose calculated based on concentration of the drug in the patient's bloodstream and the concentration of the drug that was actually measured in the patient's bloodstream (measured CPSS), The Measured Steady State Concentration Plasma is the actual concentration of the drug that is measured in the patient's bloodstream through therapeutic drug monitoring & The Target Steady State Plasma Concentration represents the therapeutic range or the optimal concentration that is expected to provide the desired therapeutic effect.

How to calculate Previous Rate of Drug Dose given Revised Dose?

The Previous Rate of Drug Dose given Revised Dose formula is defined as the ratio of the product of the revised dose and measured steady state plasma concentration to the target steady state plasma concentration is calculated using Previous Rate of Dose = (Revised Dose*Measured Steady State Concentration Plasma)/(Target Steady State Plasma Concentration). To calculate Previous Rate of Drug Dose given Revised Dose, you need Revised Dose (RD), Measured Steady State Concentration Plasma (M_cpss) & Target Steady State Plasma Concentration (T_cpss). With our tool, you need to enter the respective value for Revised Dose, Measured Steady State Concentration Plasma & Target Steady State Plasma Concentration and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

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