Modifying Factor of Enzyme Calculator

✖The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.ⓘ Inhibitor Concentration [I]			+10% -10%
✖The Enzyme Inhibitor Dissociation Constant is measured by the method in which the inhibitor is titrated into a solution of enzyme and the heat released or absorbed is measured.ⓘ Enzyme Inhibitor Dissociation Constant [K_i]			+10% -10%

✖The Enzyme Modifying Factor is defined by the inhibitor concentration and the dissociation constants of enzyme.ⓘ Modifying Factor of Enzyme [α]

⎘ Copy

👎

Formula

LaTeX

Reset

👍

Download Chemical Kinetics Formula PDF PDF Image

Modifying Factor of Enzyme Solution

STEP 0: Pre-Calculation Summary

Formula Used

Enzyme Modifying Factor = 1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant)
α = 1+(I/K_i)
This formula uses 3 Variables

Variables Used

Enzyme Modifying Factor - The Enzyme Modifying Factor is defined by the inhibitor concentration and the dissociation constants of enzyme.
Inhibitor Concentration - (Measured in Mole per Cubic Meter) - The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.
Enzyme Inhibitor Dissociation Constant - (Measured in Mole per Cubic Meter) - The Enzyme Inhibitor Dissociation Constant is measured by the method in which the inhibitor is titrated into a solution of enzyme and the heat released or absorbed is measured.

STEP 1: Convert Input(s) to Base Unit

Inhibitor Concentration: 9 Mole per Liter --> 9000 Mole per Cubic Meter (Check conversion here)
Enzyme Inhibitor Dissociation Constant: 19 Mole per Liter --> 19000 Mole per Cubic Meter (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

α = 1+(I/K_i) --> 1+(9000/19000)

Evaluating ... ...

α = 1.47368421052632

STEP 3: Convert Result to Output's Unit

1.47368421052632 --> No Conversion Required

FINAL ANSWER

1.47368421052632 ≈ 1.473684 <-- Enzyme Modifying Factor

(Calculation completed in 00.020 seconds)

You are here -

Home » Chemistry » Chemical Kinetics » Enzyme Kinetics » Competitive Inhibitor » Modifying Factor of Enzyme

Credits

Created by Prashant Singh

K J Somaiya College of science (K J Somaiya), Mumbai

Prashant Singh has created this Calculator and 700+ more calculators!

Verified by Prerana Bakli

University of Hawaiʻi at Mānoa (UH Manoa), Hawaii, USA

Prerana Bakli has verified this Calculator and 1600+ more calculators!

< Competitive Inhibitor Calculators

Substrate Concentration of Competitive Inhibition of Enzyme Catalysis

LaTeX Go Substrate Concentration = (Initial Reaction Rate*(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))))/((Final Rate Constant*Initial Enzyme Concentration)-Initial Reaction Rate)

Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration

LaTeX Go Substrate Concentration = (Enzyme Substrate Complex Concentration*(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))))/((Initial Enzyme Concentration)-Enzyme Substrate Complex Concentration)

Substrate Concentration in Competitive Inhibition given Maximum Rate of System

LaTeX Go Substrate Concentration = (Initial Reaction Rate*(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))))/(Maximum Rate-Initial Reaction Rate)

Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition

LaTeX Go Apparent Michaelis Constant = (Substrate Concentration*(Maximum Rate-Initial Reaction Rate))/Initial Reaction Rate

Modifying Factor of Enzyme Formula

LaTeX Go

Enzyme Modifying Factor = 1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant)
α = 1+(I/K_i)

What is competitive Inhibition?

In competitive inhibition, the substrate and inhibitor cannot bind to the enzyme at the same time,this usually results from the inhibitor having an affinity for the active site of an enzyme where the substrate also binds; the substrate and inhibitor compete for access to the enzyme's active site.This type of inhibition can overcome by sufficiently high concentrations of substrate (Vmax remains constant), i.e., by out-competing the inhibitor. However, the apparent Km will increase as it takes a higher concentration of the substrate to reach the Km point, or half the Vmax. Competitive inhibitors are often similar in structure to the real substrate.

How to Calculate Modifying Factor of Enzyme?

Modifying Factor of Enzyme calculator uses Enzyme Modifying Factor = 1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant) to calculate the Enzyme Modifying Factor, The Modifying factor of enzyme formula is defined as the relation with inhibitor concentration and with the enzyme inhibitor dissociation constant. Enzyme Modifying Factor is denoted by α symbol.

How to calculate Modifying Factor of Enzyme using this online calculator? To use this online calculator for Modifying Factor of Enzyme, enter Inhibitor Concentration (I) & Enzyme Inhibitor Dissociation Constant (K_i) and hit the calculate button. Here is how the Modifying Factor of Enzyme calculation can be explained with given input values -> 1.473684 = 1+(9000/19000).

FAQ

What is Modifying Factor of Enzyme?

The Modifying factor of enzyme formula is defined as the relation with inhibitor concentration and with the enzyme inhibitor dissociation constant and is represented as α = 1+(I/K_i) or Enzyme Modifying Factor = 1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant). The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system & The Enzyme Inhibitor Dissociation Constant is measured by the method in which the inhibitor is titrated into a solution of enzyme and the heat released or absorbed is measured.

How to calculate Modifying Factor of Enzyme?

The Modifying factor of enzyme formula is defined as the relation with inhibitor concentration and with the enzyme inhibitor dissociation constant is calculated using Enzyme Modifying Factor = 1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant). To calculate Modifying Factor of Enzyme, you need Inhibitor Concentration (I) & Enzyme Inhibitor Dissociation Constant (K_i). With our tool, you need to enter the respective value for Inhibitor Concentration & Enzyme Inhibitor Dissociation Constant and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

Home

FREE PDFs

🔍 Search