Measured Steady State Concentration of Plasma Solution

STEP 0: Pre-Calculation Summary
Formula Used
Measured Steady State Concentration Plasma = (Previous Rate of Dose*Target Steady State Plasma Concentration)/Revised Dose
Mcpss = (PDR*Tcpss)/RD
This formula uses 4 Variables
Variables Used
Measured Steady State Concentration Plasma - (Measured in Kilogram per Cubic Meter) - The Measured Steady State Concentration Plasma is the actual concentration of the drug that is measured in the patient's bloodstream through therapeutic drug monitoring.
Previous Rate of Dose - (Measured in Kilogram) - Previous Rate of Dose Rate is the dose of the medication that the patient was previously receiving.
Target Steady State Plasma Concentration - (Measured in Kilogram per Cubic Meter) - The Target Steady State Plasma Concentration represents the therapeutic range or the optimal concentration that is expected to provide the desired therapeutic effect.
Revised Dose - (Measured in Kilogram) - The Revised dose calculated based on concentration of the drug in the patient's bloodstream and the concentration of the drug that was actually measured in the patient's bloodstream (measured CPSS).
STEP 1: Convert Input(s) to Base Unit
Previous Rate of Dose: 100 Kilogram --> 100 Kilogram No Conversion Required
Target Steady State Plasma Concentration: 10 Milligram per Liter --> 0.01 Kilogram per Cubic Meter (Check conversion ​here)
Revised Dose: 200 Milligram --> 0.0002 Kilogram (Check conversion ​here)
STEP 2: Evaluate Formula
Substituting Input Values in Formula
Mcpss = (PDR*Tcpss)/RD --> (100*0.01)/0.0002
Evaluating ... ...
Mcpss = 5000
STEP 3: Convert Result to Output's Unit
5000 Kilogram per Cubic Meter -->5000000 Milligram per Liter (Check conversion ​here)
FINAL ANSWER
5000000 5E+6 Milligram per Liter <-- Measured Steady State Concentration Plasma
(Calculation completed in 00.006 seconds)

Credits

Creator Image
Created by Ritacheta Sen
University of Calcutta (C.U), Kolkata
Ritacheta Sen has created this Calculator and 25+ more calculators!
Verifier Image
Verified by Soupayan banerjee
National University of Judicial Science (NUJS), Kolkata
Soupayan banerjee has verified this Calculator and 900+ more calculators!

Dose Calculators

Dose given volume of distribution and area under curve
​ LaTeX ​ Go Dose = Volume of Distribution*Elimination Rate Constant*Area Under Curve
Amount of drug administered given apparent volume
​ LaTeX ​ Go Dose = Volume of Distribution*Concentration of Drug
Amount of drug in given volume of plasma
​ LaTeX ​ Go Concentration of Drug = Dose/Volume of Distribution
Amount of drug administered given area under curve
​ LaTeX ​ Go Dose = Volume of Plasma Cleared*Area Under Curve

Measured Steady State Concentration of Plasma Formula

​LaTeX ​Go
Measured Steady State Concentration Plasma = (Previous Rate of Dose*Target Steady State Plasma Concentration)/Revised Dose
Mcpss = (PDR*Tcpss)/RD

How does the concentration of reactants affect the rate of reaction?

According to the collision theory, the rate of reaction increases with the increase in the concentration of the reactants.
As per the law of mass action, the chemical reaction rate is directly proportional to the concentration of reactants.
This implies that the chemical reaction rate increases with the increase in concentration and decreases with the decrease in the concentration of reactants.
Time plays a major role in changing the concentration of reactants and products. Therefore, even time is a vital factor affecting the reaction rate.

How to Calculate Measured Steady State Concentration of Plasma?

Measured Steady State Concentration of Plasma calculator uses Measured Steady State Concentration Plasma = (Previous Rate of Dose*Target Steady State Plasma Concentration)/Revised Dose to calculate the Measured Steady State Concentration Plasma, The Measured Steady State Concentration of Plasma formula is defined as the ratio of the product of the previous dose rate and target steady state plasma concentration to the revised dose. Measured Steady State Concentration Plasma is denoted by Mcpss symbol.

How to calculate Measured Steady State Concentration of Plasma using this online calculator? To use this online calculator for Measured Steady State Concentration of Plasma, enter Previous Rate of Dose (PDR), Target Steady State Plasma Concentration (Tcpss) & Revised Dose (RD) and hit the calculate button. Here is how the Measured Steady State Concentration of Plasma calculation can be explained with given input values -> 5E+9 = (100*0.01)/0.0002.

FAQ

What is Measured Steady State Concentration of Plasma?
The Measured Steady State Concentration of Plasma formula is defined as the ratio of the product of the previous dose rate and target steady state plasma concentration to the revised dose and is represented as Mcpss = (PDR*Tcpss)/RD or Measured Steady State Concentration Plasma = (Previous Rate of Dose*Target Steady State Plasma Concentration)/Revised Dose. Previous Rate of Dose Rate is the dose of the medication that the patient was previously receiving, The Target Steady State Plasma Concentration represents the therapeutic range or the optimal concentration that is expected to provide the desired therapeutic effect & The Revised dose calculated based on concentration of the drug in the patient's bloodstream and the concentration of the drug that was actually measured in the patient's bloodstream (measured CPSS).
How to calculate Measured Steady State Concentration of Plasma?
The Measured Steady State Concentration of Plasma formula is defined as the ratio of the product of the previous dose rate and target steady state plasma concentration to the revised dose is calculated using Measured Steady State Concentration Plasma = (Previous Rate of Dose*Target Steady State Plasma Concentration)/Revised Dose. To calculate Measured Steady State Concentration of Plasma, you need Previous Rate of Dose (PDR), Target Steady State Plasma Concentration (Tcpss) & Revised Dose (RD). With our tool, you need to enter the respective value for Previous Rate of Dose, Target Steady State Plasma Concentration & Revised Dose and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
Let Others Know
Facebook
Twitter
Reddit
LinkedIn
Email
WhatsApp
Copied!