What is Pharmacokinetics?
Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.
How to Calculate Lowest Plasma Concentration Given Peak through Fluctuation?
Lowest Plasma Concentration Given Peak through Fluctuation calculator uses Lowest Plasma Concentration = Peak Plasma Concentration-(Average Plasma Concentration*Peak Through Fluctuation) to calculate the Lowest Plasma Concentration, The Lowest Plasma Concentration Given Peak through Fluctuation formula is defined as the subtraction of average plasma concentration and peak fluctuation from the peak plasma concentration of drugs. Lowest Plasma Concentration is denoted by Cmin symbol.
How to calculate Lowest Plasma Concentration Given Peak through Fluctuation using this online calculator? To use this online calculator for Lowest Plasma Concentration Given Peak through Fluctuation, enter Peak Plasma Concentration (Cmax), Average Plasma Concentration (Cav) & Peak Through Fluctuation (%PTF) and hit the calculate button. Here is how the Lowest Plasma Concentration Given Peak through Fluctuation calculation can be explained with given input values -> 0.052524 = 60900-(20000*0.4188).