Inhibitor Concentration given Modifying Factor of Enzyme Calculator

✖The Enzyme Modifying Factor is defined by the inhibitor concentration and the dissociation constants of enzyme.ⓘ Enzyme Modifying Factor [α]			+10% -10%
✖The Enzyme Inhibitor Dissociation Constant is measured by the method in which the inhibitor is titrated into a solution of enzyme and the heat released or absorbed is measured.ⓘ Enzyme Inhibitor Dissociation Constant [K_i]			+10% -10%

✖The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.ⓘ Inhibitor Concentration given Modifying Factor of Enzyme [I]

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Inhibitor Concentration given Modifying Factor of Enzyme Solution

STEP 0: Pre-Calculation Summary

Formula Used

Inhibitor Concentration = (Enzyme Modifying Factor-1)*Enzyme Inhibitor Dissociation Constant
I = (α-1)*K_i
This formula uses 3 Variables

Variables Used

Inhibitor Concentration - (Measured in Mole per Cubic Meter) - The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.
Enzyme Modifying Factor - The Enzyme Modifying Factor is defined by the inhibitor concentration and the dissociation constants of enzyme.
Enzyme Inhibitor Dissociation Constant - (Measured in Mole per Cubic Meter) - The Enzyme Inhibitor Dissociation Constant is measured by the method in which the inhibitor is titrated into a solution of enzyme and the heat released or absorbed is measured.

STEP 1: Convert Input(s) to Base Unit

Enzyme Modifying Factor: 5 --> No Conversion Required
Enzyme Inhibitor Dissociation Constant: 19 Mole per Liter --> 19000 Mole per Cubic Meter (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

I = (α-1)*K_i --> (5-1)*19000

Evaluating ... ...

I = 76000

STEP 3: Convert Result to Output's Unit

76000 Mole per Cubic Meter -->76 Mole per Liter (Check conversion here)

FINAL ANSWER

76 Mole per Liter <-- Inhibitor Concentration

(Calculation completed in 00.020 seconds)

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< Complex Concentration Calculators

Substrate Concentration given Catalytic Rate Constant and Initial Enzyme Concentration

LaTeX Go Concentration of Substrate = (Michaelis Constant*Initial Reaction Rate)/((Catalytic Rate Constant*Initial Enzyme Concentration)-Initial Reaction Rate)

Substrate Concentration if Michaelis Constant is very Large than Substrate Concentration

LaTeX Go Substrate Concentration = (Initial Reaction Rate*Michaelis Constant)/(Catalytic Rate Constant*Initial Enzyme Concentration)

Initial Enzyme Concentration at Low Substrate Concentration

LaTeX Go Initial Enzyme Concentration = (Initial Reaction Rate*Michaelis Constant)/(Catalytic Rate Constant*Substrate Concentration)

Substrate Concentration given Maximum Rate at Low Concentration

LaTeX Go Substrate Concentration = (Initial Reaction Rate*Michaelis Constant)/Maximum Rate

Inhibitor Concentration given Modifying Factor of Enzyme Formula

LaTeX Go

Inhibitor Concentration = (Enzyme Modifying Factor-1)*Enzyme Inhibitor Dissociation Constant
I = (α-1)*K_i

What is competitive Inhibition?

In competitive inhibition, the substrate and inhibitor cannot bind to the enzyme at the same time, as shown in the figure on the right. This usually results from the inhibitor having an affinity for the active site of an enzyme where the substrate also binds; the substrate and inhibitor compete for access to the enzyme's active site. This type of inhibition can be overcome by sufficiently high concentrations of substrate (Vmax remains constant), i.e., by out-competing the inhibitor. However, the apparent Km will increase as it takes a higher concentration of the substrate to reach the Km point, or half the Vmax. Competitive inhibitors are often similar in structure to the real substrate.

How to Calculate Inhibitor Concentration given Modifying Factor of Enzyme?

Inhibitor Concentration given Modifying Factor of Enzyme calculator uses Inhibitor Concentration = (Enzyme Modifying Factor-1)*Enzyme Inhibitor Dissociation Constant to calculate the Inhibitor Concentration, The Inhibitor concentration given modifying factor of enzyme formula is defined as the relation with modifying factor of enzyme and with the enzyme inhibitor dissociation constant. Inhibitor Concentration is denoted by I symbol.

How to calculate Inhibitor Concentration given Modifying Factor of Enzyme using this online calculator? To use this online calculator for Inhibitor Concentration given Modifying Factor of Enzyme, enter Enzyme Modifying Factor (α) & Enzyme Inhibitor Dissociation Constant (K_i) and hit the calculate button. Here is how the Inhibitor Concentration given Modifying Factor of Enzyme calculation can be explained with given input values -> 0.076 = (5-1)*19000.

FAQ

What is Inhibitor Concentration given Modifying Factor of Enzyme?

The Inhibitor concentration given modifying factor of enzyme formula is defined as the relation with modifying factor of enzyme and with the enzyme inhibitor dissociation constant and is represented as I = (α-1)*K_i or Inhibitor Concentration = (Enzyme Modifying Factor-1)*Enzyme Inhibitor Dissociation Constant. The Enzyme Modifying Factor is defined by the inhibitor concentration and the dissociation constants of enzyme & The Enzyme Inhibitor Dissociation Constant is measured by the method in which the inhibitor is titrated into a solution of enzyme and the heat released or absorbed is measured.

How to calculate Inhibitor Concentration given Modifying Factor of Enzyme?

The Inhibitor concentration given modifying factor of enzyme formula is defined as the relation with modifying factor of enzyme and with the enzyme inhibitor dissociation constant is calculated using Inhibitor Concentration = (Enzyme Modifying Factor-1)*Enzyme Inhibitor Dissociation Constant. To calculate Inhibitor Concentration given Modifying Factor of Enzyme, you need Enzyme Modifying Factor (α) & Enzyme Inhibitor Dissociation Constant (K_i). With our tool, you need to enter the respective value for Enzyme Modifying Factor & Enzyme Inhibitor Dissociation Constant and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Inhibitor Concentration?

In this formula, Inhibitor Concentration uses Enzyme Modifying Factor & Enzyme Inhibitor Dissociation Constant. We can use 2 other way(s) to calculate the same, which is/are as follows -

Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant
Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant

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