Inhibitor Concentration given Enzyme Substrate Modifying Factor Calculator

✖The Enzyme Substrate Modifying Factor is defined by the inhibitor concentration and the dissociation constant of the enzyme-substrate complex.ⓘ Enzyme Substrate Modifying Factor [α^']			+10% -10%
✖The Enzyme Substrate Dissociation Constant is difficult to measure directly since the enzyme-substrate complex is short-lived and undergoes a chemical reaction to form the product.ⓘ Enzyme Substrate Dissociation Constant [K_i']			+10% -10%

✖The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.ⓘ Inhibitor Concentration given Enzyme Substrate Modifying Factor [I]

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Inhibitor Concentration given Enzyme Substrate Modifying Factor Solution

STEP 0: Pre-Calculation Summary

Formula Used

Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant
I = (α^'-1)*K_i'
This formula uses 3 Variables

Variables Used

Inhibitor Concentration - (Measured in Mole per Cubic Meter) - The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.
Enzyme Substrate Modifying Factor - The Enzyme Substrate Modifying Factor is defined by the inhibitor concentration and the dissociation constant of the enzyme-substrate complex.
Enzyme Substrate Dissociation Constant - (Measured in Mole per Cubic Meter) - The Enzyme Substrate Dissociation Constant is difficult to measure directly since the enzyme-substrate complex is short-lived and undergoes a chemical reaction to form the product.

STEP 1: Convert Input(s) to Base Unit

Enzyme Substrate Modifying Factor: 2 --> No Conversion Required
Enzyme Substrate Dissociation Constant: 15 Mole per Liter --> 15000 Mole per Cubic Meter (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

I = (α^'-1)*K_i' --> (2-1)*15000

Evaluating ... ...

I = 15000

STEP 3: Convert Result to Output's Unit

15000 Mole per Cubic Meter -->15 Mole per Liter (Check conversion here)

FINAL ANSWER

15 Mole per Liter <-- Inhibitor Concentration

(Calculation completed in 00.004 seconds)

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< Important Formulas on Enzyme Kinetics Calculators

Initial Reaction Rate given Dissociation Rate Constant

LaTeX Go Initial Reaction Rate given DRC = (Maximum Rate*Substrate Concentration)/(Dissociation Rate Constant+Substrate Concentration)

Maximum Rate given Dissociation Rate Constant

LaTeX Go Maximum Rate given DRC = (Initial Reaction Rate*(Dissociation Rate Constant+Substrate Concentration))/Substrate Concentration

Modifying Factor of Enzyme Substrate Complex

LaTeX Go Enzyme Substrate Modifying Factor = 1+(Inhibitor Concentration/Enzyme Substrate Dissociation Constant)

Initial Rate of System given Rate Constant and Enzyme Substrate Complex Concentration

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Inhibitor Concentration given Enzyme Substrate Modifying Factor Formula

LaTeX Go

Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant
I = (α^'-1)*K_i'

What is Uncompetitive inhibitor?

Uncompetitive inhibition, also known as anti-competitive inhibition, takes place when an enzyme inhibitor binds only to the complex formed between the enzyme and the substrate (the E-S complex). Uncompetitive inhibition typically occurs in reactions with two or more substrates or products. Uncompetitive inhibition is distinguished from competitive inhibition by two observations: first uncompetitive inhibition cannot be reversed by increasing [S] and second, the Lineweaver–Burk plot yields parallel rather than intersecting lines.

How to Calculate Inhibitor Concentration given Enzyme Substrate Modifying Factor?

Inhibitor Concentration given Enzyme Substrate Modifying Factor calculator uses Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant to calculate the Inhibitor Concentration, The Inhibitor concentration given Enzyme substrate modifying factor formula is defined as the relation with the enzyme-substrate dissociation constant and modifying factor. Inhibitor Concentration is denoted by I symbol.

How to calculate Inhibitor Concentration given Enzyme Substrate Modifying Factor using this online calculator? To use this online calculator for Inhibitor Concentration given Enzyme Substrate Modifying Factor, enter Enzyme Substrate Modifying Factor (α^') & Enzyme Substrate Dissociation Constant (K_i') and hit the calculate button. Here is how the Inhibitor Concentration given Enzyme Substrate Modifying Factor calculation can be explained with given input values -> 0.015 = (2-1)*15000.

FAQ

What is Inhibitor Concentration given Enzyme Substrate Modifying Factor?

The Inhibitor concentration given Enzyme substrate modifying factor formula is defined as the relation with the enzyme-substrate dissociation constant and modifying factor and is represented as I = (α^'-1)*K_i' or Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant. The Enzyme Substrate Modifying Factor is defined by the inhibitor concentration and the dissociation constant of the enzyme-substrate complex & The Enzyme Substrate Dissociation Constant is difficult to measure directly since the enzyme-substrate complex is short-lived and undergoes a chemical reaction to form the product.

How to calculate Inhibitor Concentration given Enzyme Substrate Modifying Factor?

The Inhibitor concentration given Enzyme substrate modifying factor formula is defined as the relation with the enzyme-substrate dissociation constant and modifying factor is calculated using Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant. To calculate Inhibitor Concentration given Enzyme Substrate Modifying Factor, you need Enzyme Substrate Modifying Factor (α^') & Enzyme Substrate Dissociation Constant (K_i'). With our tool, you need to enter the respective value for Enzyme Substrate Modifying Factor & Enzyme Substrate Dissociation Constant and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Inhibitor Concentration?

In this formula, Inhibitor Concentration uses Enzyme Substrate Modifying Factor & Enzyme Substrate Dissociation Constant. We can use 2 other way(s) to calculate the same, which is/are as follows -

Inhibitor Concentration = (Enzyme Modifying Factor-1)*Enzyme Inhibitor Dissociation Constant
Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant

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