Inhibitor Concentration given Modifying Factor of Enzyme Substrate Complex Calculator

✖The Enzyme Substrate Modifying Factor is defined by the inhibitor concentration and the dissociation constant of the enzyme-substrate complex.ⓘ Enzyme Substrate Modifying Factor [α^']			+10% -10%
✖The Enzyme Substrate Dissociation Constant is difficult to measure directly since the enzyme-substrate complex is short-lived and undergoes a chemical reaction to form the product.ⓘ Enzyme Substrate Dissociation Constant [K_i']			+10% -10%

✖The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.ⓘ Inhibitor Concentration given Modifying Factor of Enzyme Substrate Complex [I]

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Inhibitor Concentration given Modifying Factor of Enzyme Substrate Complex Solution

STEP 0: Pre-Calculation Summary

Formula Used

Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant
I = (α^'-1)*K_i'
This formula uses 3 Variables

Variables Used

Inhibitor Concentration - (Measured in Mole per Cubic Meter) - The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.
Enzyme Substrate Modifying Factor - The Enzyme Substrate Modifying Factor is defined by the inhibitor concentration and the dissociation constant of the enzyme-substrate complex.
Enzyme Substrate Dissociation Constant - (Measured in Mole per Cubic Meter) - The Enzyme Substrate Dissociation Constant is difficult to measure directly since the enzyme-substrate complex is short-lived and undergoes a chemical reaction to form the product.

STEP 1: Convert Input(s) to Base Unit

Enzyme Substrate Modifying Factor: 2 --> No Conversion Required
Enzyme Substrate Dissociation Constant: 15 Mole per Liter --> 15000 Mole per Cubic Meter (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

I = (α^'-1)*K_i' --> (2-1)*15000

Evaluating ... ...

I = 15000

STEP 3: Convert Result to Output's Unit

15000 Mole per Cubic Meter -->15 Mole per Liter (Check conversion here)

FINAL ANSWER

15 Mole per Liter <-- Inhibitor Concentration

(Calculation completed in 00.020 seconds)

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< Complex Concentration Calculators

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LaTeX Go Initial Enzyme Concentration = (Initial Reaction Rate*Michaelis Constant)/(Catalytic Rate Constant*Substrate Concentration)

Substrate Concentration given Maximum Rate at Low Concentration

LaTeX Go Substrate Concentration = (Initial Reaction Rate*Michaelis Constant)/Maximum Rate

Inhibitor Concentration given Modifying Factor of Enzyme Substrate Complex Formula

LaTeX Go

Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant
I = (α^'-1)*K_i'

What is competitive Inhibition?

In competitive inhibition, the substrate and inhibitor cannot bind to the enzyme at the same time, as shown in the figure on the right. This usually results from the inhibitor having an affinity for the active site of an enzyme where the substrate also binds; the substrate and inhibitor compete for access to the enzyme's active site. This type of inhibition can be overcome by sufficiently high concentrations of substrate (Vmax remains constant), i.e., by out-competing the inhibitor. However, the apparent Km will increase as it takes a higher concentration of the substrate to reach the Km point, or half the Vmax. Competitive inhibitors are often similar in structure to the real substrate.

How to Calculate Inhibitor Concentration given Modifying Factor of Enzyme Substrate Complex?

Inhibitor Concentration given Modifying Factor of Enzyme Substrate Complex calculator uses Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant to calculate the Inhibitor Concentration, The Inhibitor concentration given modifying factor of enzyme substrate complex formula is defined as the relation with the modifying factor of enzyme-substrate complex and with a dissociation constant of enzyme-substrate complex of the system. Inhibitor Concentration is denoted by I symbol.

How to calculate Inhibitor Concentration given Modifying Factor of Enzyme Substrate Complex using this online calculator? To use this online calculator for Inhibitor Concentration given Modifying Factor of Enzyme Substrate Complex, enter Enzyme Substrate Modifying Factor (α^') & Enzyme Substrate Dissociation Constant (K_i') and hit the calculate button. Here is how the Inhibitor Concentration given Modifying Factor of Enzyme Substrate Complex calculation can be explained with given input values -> 0.015 = (2-1)*15000.

FAQ

What is Inhibitor Concentration given Modifying Factor of Enzyme Substrate Complex?

The Inhibitor concentration given modifying factor of enzyme substrate complex formula is defined as the relation with the modifying factor of enzyme-substrate complex and with a dissociation constant of enzyme-substrate complex of the system and is represented as I = (α^'-1)*K_i' or Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant. The Enzyme Substrate Modifying Factor is defined by the inhibitor concentration and the dissociation constant of the enzyme-substrate complex & The Enzyme Substrate Dissociation Constant is difficult to measure directly since the enzyme-substrate complex is short-lived and undergoes a chemical reaction to form the product.

How to calculate Inhibitor Concentration given Modifying Factor of Enzyme Substrate Complex?

The Inhibitor concentration given modifying factor of enzyme substrate complex formula is defined as the relation with the modifying factor of enzyme-substrate complex and with a dissociation constant of enzyme-substrate complex of the system is calculated using Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant. To calculate Inhibitor Concentration given Modifying Factor of Enzyme Substrate Complex, you need Enzyme Substrate Modifying Factor (α^') & Enzyme Substrate Dissociation Constant (K_i'). With our tool, you need to enter the respective value for Enzyme Substrate Modifying Factor & Enzyme Substrate Dissociation Constant and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Inhibitor Concentration?

In this formula, Inhibitor Concentration uses Enzyme Substrate Modifying Factor & Enzyme Substrate Dissociation Constant. We can use 2 other way(s) to calculate the same, which is/are as follows -

Inhibitor Concentration = (Enzyme Modifying Factor-1)*Enzyme Inhibitor Dissociation Constant
Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant

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