Inhibitor Concentration given Modifying Factor of Enzyme Solution

STEP 0: Pre-Calculation Summary
Formula Used
Inhibitor Concentration = (Enzyme Modifying Factor-1)*Enzyme Inhibitor Dissociation Constant
I = (α-1)*Ki
This formula uses 3 Variables
Variables Used
Inhibitor Concentration - (Measured in Mole per Cubic Meter) - The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.
Enzyme Modifying Factor - The Enzyme Modifying Factor is defined by the inhibitor concentration and the dissociation constants of enzyme.
Enzyme Inhibitor Dissociation Constant - (Measured in Mole per Cubic Meter) - The Enzyme Inhibitor Dissociation Constant is measured by the method in which the inhibitor is titrated into a solution of enzyme and the heat released or absorbed is measured.
STEP 1: Convert Input(s) to Base Unit
Enzyme Modifying Factor: 5 --> No Conversion Required
Enzyme Inhibitor Dissociation Constant: 19 Mole per Liter --> 19000 Mole per Cubic Meter (Check conversion ​here)
STEP 2: Evaluate Formula
Substituting Input Values in Formula
I = (α-1)*Ki --> (5-1)*19000
Evaluating ... ...
I = 76000
STEP 3: Convert Result to Output's Unit
76000 Mole per Cubic Meter -->76 Mole per Liter (Check conversion ​here)
FINAL ANSWER
76 Mole per Liter <-- Inhibitor Concentration
(Calculation completed in 00.004 seconds)

Credits

Creator Image
Created by Prashant Singh
K J Somaiya College of science (K J Somaiya), Mumbai
Prashant Singh has created this Calculator and 700+ more calculators!
Verifier Image
Verified by Prerana Bakli
University of Hawaiʻi at Mānoa (UH Manoa), Hawaii, USA
Prerana Bakli has verified this Calculator and 1600+ more calculators!

Complex Concentration Calculators

Substrate Concentration given Catalytic Rate Constant and Initial Enzyme Concentration
​ LaTeX ​ Go Concentration of Substrate = (Michaelis Constant*Initial Reaction Rate)/((Catalytic Rate Constant*Initial Enzyme Concentration)-Initial Reaction Rate)
Substrate Concentration if Michaelis Constant is very Large than Substrate Concentration
​ LaTeX ​ Go Substrate Concentration = (Initial Reaction Rate*Michaelis Constant)/(Catalytic Rate Constant*Initial Enzyme Concentration)
Initial Enzyme Concentration at Low Substrate Concentration
​ LaTeX ​ Go Initial Enzyme Concentration = (Initial Reaction Rate*Michaelis Constant)/(Catalytic Rate Constant*Substrate Concentration)
Substrate Concentration given Maximum Rate at Low Concentration
​ LaTeX ​ Go Substrate Concentration = (Initial Reaction Rate*Michaelis Constant)/Maximum Rate

Inhibitor Concentration given Modifying Factor of Enzyme Formula

​LaTeX ​Go
Inhibitor Concentration = (Enzyme Modifying Factor-1)*Enzyme Inhibitor Dissociation Constant
I = (α-1)*Ki

What is competitive Inhibition?

In competitive inhibition, the substrate and inhibitor cannot bind to the enzyme at the same time, as shown in the figure on the right. This usually results from the inhibitor having an affinity for the active site of an enzyme where the substrate also binds; the substrate and inhibitor compete for access to the enzyme's active site. This type of inhibition can be overcome by sufficiently high concentrations of substrate (Vmax remains constant), i.e., by out-competing the inhibitor. However, the apparent Km will increase as it takes a higher concentration of the substrate to reach the Km point, or half the Vmax. Competitive inhibitors are often similar in structure to the real substrate.

How to Calculate Inhibitor Concentration given Modifying Factor of Enzyme?

Inhibitor Concentration given Modifying Factor of Enzyme calculator uses Inhibitor Concentration = (Enzyme Modifying Factor-1)*Enzyme Inhibitor Dissociation Constant to calculate the Inhibitor Concentration, The Inhibitor concentration given modifying factor of enzyme formula is defined as the relation with modifying factor of enzyme and with the enzyme inhibitor dissociation constant. Inhibitor Concentration is denoted by I symbol.

How to calculate Inhibitor Concentration given Modifying Factor of Enzyme using this online calculator? To use this online calculator for Inhibitor Concentration given Modifying Factor of Enzyme, enter Enzyme Modifying Factor (α) & Enzyme Inhibitor Dissociation Constant (Ki) and hit the calculate button. Here is how the Inhibitor Concentration given Modifying Factor of Enzyme calculation can be explained with given input values -> 0.076 = (5-1)*19000.

FAQ

What is Inhibitor Concentration given Modifying Factor of Enzyme?
The Inhibitor concentration given modifying factor of enzyme formula is defined as the relation with modifying factor of enzyme and with the enzyme inhibitor dissociation constant and is represented as I = (α-1)*Ki or Inhibitor Concentration = (Enzyme Modifying Factor-1)*Enzyme Inhibitor Dissociation Constant. The Enzyme Modifying Factor is defined by the inhibitor concentration and the dissociation constants of enzyme & The Enzyme Inhibitor Dissociation Constant is measured by the method in which the inhibitor is titrated into a solution of enzyme and the heat released or absorbed is measured.
How to calculate Inhibitor Concentration given Modifying Factor of Enzyme?
The Inhibitor concentration given modifying factor of enzyme formula is defined as the relation with modifying factor of enzyme and with the enzyme inhibitor dissociation constant is calculated using Inhibitor Concentration = (Enzyme Modifying Factor-1)*Enzyme Inhibitor Dissociation Constant. To calculate Inhibitor Concentration given Modifying Factor of Enzyme, you need Enzyme Modifying Factor (α) & Enzyme Inhibitor Dissociation Constant (Ki). With our tool, you need to enter the respective value for Enzyme Modifying Factor & Enzyme Inhibitor Dissociation Constant and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
How many ways are there to calculate Inhibitor Concentration?
In this formula, Inhibitor Concentration uses Enzyme Modifying Factor & Enzyme Inhibitor Dissociation Constant. We can use 2 other way(s) to calculate the same, which is/are as follows -
  • Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant
  • Inhibitor Concentration = (Enzyme Substrate Modifying Factor-1)*Enzyme Substrate Dissociation Constant
Let Others Know
Facebook
Twitter
Reddit
LinkedIn
Email
WhatsApp
Copied!