Filtration Rate of Drug Solution

STEP 0: Pre-Calculation Summary
Formula Used
Filtration Rate = ((Renal Clearance*Plasma Concentration)+Reabsorption Rate of Drug-Secretion Rate of Drug)
Frate = ((CLr*Cp)+Rrate-Srate)
This formula uses 5 Variables
Variables Used
Filtration Rate - (Measured in Cubic meter per second) - Filtration Rate is the estimates of how much blood passes through the glomeruli each minute.
Renal Clearance - (Measured in Cubic Meter per Second) - Renal Clearance is a measure of kidney transport in units of volume of plasma per unit time.
Plasma Concentration - (Measured in Mole per Cubic Meter) - Plasma Concentration is the concentration of the drug after administration and before the next dose is administered.
Reabsorption Rate of Drug - (Measured in Cubic meter per second) - Reabsorption Rate of Drug is the measure of movement of drug and solutes from the tubule back into the plasma.
Secretion Rate of Drug - (Measured in Cubic meter per second) - Secretion Rate of Drug is the measure of the removal of drugs from the body, either as a metabolite or unchanged drug.
STEP 1: Convert Input(s) to Base Unit
Renal Clearance: 15.6 Milliliter per Minute --> 2.6E-07 Cubic Meter per Second (Check conversion ​here)
Plasma Concentration: 17 Mole per Liter --> 17000 Mole per Cubic Meter (Check conversion ​here)
Reabsorption Rate of Drug: 14.5 Milliliter per Minute --> 2.41666666666667E-07 Cubic meter per second (Check conversion ​here)
Secretion Rate of Drug: 10.4 Milliliter per Minute --> 1.73333333333333E-07 Cubic meter per second (Check conversion ​here)
STEP 2: Evaluate Formula
Substituting Input Values in Formula
Frate = ((CLr*Cp)+Rrate-Srate) --> ((2.6E-07*17000)+2.41666666666667E-07-1.73333333333333E-07)
Evaluating ... ...
Frate = 0.00442006833333333
STEP 3: Convert Result to Output's Unit
0.00442006833333333 Cubic meter per second -->265204.1 Milliliter per Minute (Check conversion ​here)
FINAL ANSWER
265204.1 Milliliter per Minute <-- Filtration Rate
(Calculation completed in 00.020 seconds)

Credits

Creator Image
Created by Soupayan banerjee
National University of Judicial Science (NUJS), Kolkata
Soupayan banerjee has created this Calculator and 200+ more calculators!
Verifier Image
Verified by Prerana Bakli
University of Hawaiʻi at Mānoa (UH Manoa), Hawaii, USA
Prerana Bakli has verified this Calculator and 1600+ more calculators!

Drug Content Calculators

Rate of Infusion of Drug
​ LaTeX ​ Go Rate of Infusion = Volume of Plasma Cleared*Concentration of Drug
Absorption Half-Life of Drug
​ LaTeX ​ Go Absorption Half Life = ln(2)/Absorption Rate Constant
Drug Rate Entering Body
​ LaTeX ​ Go Absorption Rate Constant = ln(2)/Absorption Half Life
Apparent Volume of Drug Distribution
​ LaTeX ​ Go Volume of Distribution = Dose/Concentration of Drug

Filtration Rate of Drug Formula

​LaTeX ​Go
Filtration Rate = ((Renal Clearance*Plasma Concentration)+Reabsorption Rate of Drug-Secretion Rate of Drug)
Frate = ((CLr*Cp)+Rrate-Srate)

What is Pharmacokinetics ?

Pharmacokinetics is currently defined as the study of the time course of drug absorption, distribution, metabolism, and excretion. Clinical pharmacokinetics is the application of pharmacokinetic principles to the safe and effective therapeutic management of drugs in an individual patient.

How to Calculate Filtration Rate of Drug?

Filtration Rate of Drug calculator uses Filtration Rate = ((Renal Clearance*Plasma Concentration)+Reabsorption Rate of Drug-Secretion Rate of Drug) to calculate the Filtration Rate, The Filtration Rate of Drug formula is defined as the volume of drug filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time. Filtration Rate is denoted by Frate symbol.

How to calculate Filtration Rate of Drug using this online calculator? To use this online calculator for Filtration Rate of Drug, enter Renal Clearance (CLr), Plasma Concentration (Cp), Reabsorption Rate of Drug (Rrate) & Secretion Rate of Drug (Srate) and hit the calculate button. Here is how the Filtration Rate of Drug calculation can be explained with given input values -> 1.6E+13 = ((2.6E-07*17000)+2.41666666666667E-07-1.73333333333333E-07).

FAQ

What is Filtration Rate of Drug?
The Filtration Rate of Drug formula is defined as the volume of drug filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time and is represented as Frate = ((CLr*Cp)+Rrate-Srate) or Filtration Rate = ((Renal Clearance*Plasma Concentration)+Reabsorption Rate of Drug-Secretion Rate of Drug). Renal Clearance is a measure of kidney transport in units of volume of plasma per unit time, Plasma Concentration is the concentration of the drug after administration and before the next dose is administered, Reabsorption Rate of Drug is the measure of movement of drug and solutes from the tubule back into the plasma & Secretion Rate of Drug is the measure of the removal of drugs from the body, either as a metabolite or unchanged drug.
How to calculate Filtration Rate of Drug?
The Filtration Rate of Drug formula is defined as the volume of drug filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time is calculated using Filtration Rate = ((Renal Clearance*Plasma Concentration)+Reabsorption Rate of Drug-Secretion Rate of Drug). To calculate Filtration Rate of Drug, you need Renal Clearance (CLr), Plasma Concentration (Cp), Reabsorption Rate of Drug (Rrate) & Secretion Rate of Drug (Srate). With our tool, you need to enter the respective value for Renal Clearance, Plasma Concentration, Reabsorption Rate of Drug & Secretion Rate of Drug and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
Let Others Know
Facebook
Twitter
Reddit
LinkedIn
Email
WhatsApp
Copied!