Enzyme Substrate Modifying Factor given Enzyme Substrate Dissociation Constant Calculator

✖The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.ⓘ Inhibitor Concentration [I]			+10% -10%
✖The Enzyme Substrate Dissociation Constant is difficult to measure directly since the enzyme-substrate complex is short-lived and undergoes a chemical reaction to form the product.ⓘ Enzyme Substrate Dissociation Constant [K_i']			+10% -10%

✖The Enzyme Substrate Modifying Factor is defined by the inhibitor concentration and the dissociation constant of the enzyme-substrate complex.ⓘ Enzyme Substrate Modifying Factor given Enzyme Substrate Dissociation Constant [α^']

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Enzyme Substrate Modifying Factor given Enzyme Substrate Dissociation Constant Solution

STEP 0: Pre-Calculation Summary

Formula Used

Enzyme Substrate Modifying Factor = (1+(Inhibitor Concentration/Enzyme Substrate Dissociation Constant))
α^' = (1+(I/K_i'))
This formula uses 3 Variables

Variables Used

Enzyme Substrate Modifying Factor - The Enzyme Substrate Modifying Factor is defined by the inhibitor concentration and the dissociation constant of the enzyme-substrate complex.
Inhibitor Concentration - (Measured in Mole per Cubic Meter) - The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.
Enzyme Substrate Dissociation Constant - (Measured in Mole per Cubic Meter) - The Enzyme Substrate Dissociation Constant is difficult to measure directly since the enzyme-substrate complex is short-lived and undergoes a chemical reaction to form the product.

STEP 1: Convert Input(s) to Base Unit

Inhibitor Concentration: 9 Mole per Liter --> 9000 Mole per Cubic Meter (Check conversion here)
Enzyme Substrate Dissociation Constant: 15 Mole per Liter --> 15000 Mole per Cubic Meter (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

α^' = (1+(I/K_i')) --> (1+(9000/15000))

Evaluating ... ...

α^' = 1.6

STEP 3: Convert Result to Output's Unit

1.6 --> No Conversion Required

FINAL ANSWER

1.6 <-- Enzyme Substrate Modifying Factor

(Calculation completed in 00.004 seconds)

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< Uncompetitive Inhibitor Calculators

Initial Reaction Rate in presence of Uncompetitive Inhibitor

LaTeX Go Initial Reaction Rate = (Maximum Rate*Substrate Concentration)/(Michaelis Constant+(Enzyme Substrate Modifying Factor*Substrate Concentration))

Maximum Reaction Rate in Presence of Uncompetitive Inhibitor

LaTeX Go Maximum Rate = (Initial Reaction Rate*(Michaelis Constant+(Enzyme Substrate Modifying Factor*Substrate Concentration)))/Substrate Concentration

Substrate Concentration in presence of Uncompetitive Inhibitor

LaTeX Go Substrate Concentration = (Michaelis Constant*Initial Reaction Rate)/(Maximum Rate-(Initial Reaction Rate*Enzyme Substrate Modifying Factor))

Michaelis Constant in Presence of Uncompetitive Inhibitor

LaTeX Go Michaelis Constant = (Substrate Concentration*(Maximum Rate-(Initial Reaction Rate*Enzyme Substrate Modifying Factor)))/Initial Reaction Rate

Enzyme Substrate Modifying Factor given Enzyme Substrate Dissociation Constant Formula

LaTeX Go

Enzyme Substrate Modifying Factor = (1+(Inhibitor Concentration/Enzyme Substrate Dissociation Constant))
α^' = (1+(I/K_i'))

What is Uncompetitive inhibitor?

Uncompetitive inhibition, also known as anti-competitive inhibition, takes place when an enzyme inhibitor binds only to the complex formed between the enzyme and the substrate (the E-S complex). Uncompetitive inhibition typically occurs in reactions with two or more substrates or products. Uncompetitive inhibition is distinguished from competitive inhibition by two observations: first uncompetitive inhibition cannot be reversed by increasing [S] and second, as shown, the Lineweaver–Burk plot yields parallel rather than intersecting lines.

How to Calculate Enzyme Substrate Modifying Factor given Enzyme Substrate Dissociation Constant?

Enzyme Substrate Modifying Factor given Enzyme Substrate Dissociation Constant calculator uses Enzyme Substrate Modifying Factor = (1+(Inhibitor Concentration/Enzyme Substrate Dissociation Constant)) to calculate the Enzyme Substrate Modifying Factor, The Enzyme substrate modifying factor given enzyme substrate dissociation constant formula is defined as the relation with the ratio of inhibitor concentration to the dissociation constant of enzyme-substrate complex. Enzyme Substrate Modifying Factor is denoted by α^' symbol.

How to calculate Enzyme Substrate Modifying Factor given Enzyme Substrate Dissociation Constant using this online calculator? To use this online calculator for Enzyme Substrate Modifying Factor given Enzyme Substrate Dissociation Constant, enter Inhibitor Concentration (I) & Enzyme Substrate Dissociation Constant (K_i') and hit the calculate button. Here is how the Enzyme Substrate Modifying Factor given Enzyme Substrate Dissociation Constant calculation can be explained with given input values -> 1.6 = (1+(9000/15000)).

FAQ

What is Enzyme Substrate Modifying Factor given Enzyme Substrate Dissociation Constant?

The Enzyme substrate modifying factor given enzyme substrate dissociation constant formula is defined as the relation with the ratio of inhibitor concentration to the dissociation constant of enzyme-substrate complex and is represented as α^' = (1+(I/K_i')) or Enzyme Substrate Modifying Factor = (1+(Inhibitor Concentration/Enzyme Substrate Dissociation Constant)). The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system & The Enzyme Substrate Dissociation Constant is difficult to measure directly since the enzyme-substrate complex is short-lived and undergoes a chemical reaction to form the product.

How to calculate Enzyme Substrate Modifying Factor given Enzyme Substrate Dissociation Constant?

The Enzyme substrate modifying factor given enzyme substrate dissociation constant formula is defined as the relation with the ratio of inhibitor concentration to the dissociation constant of enzyme-substrate complex is calculated using Enzyme Substrate Modifying Factor = (1+(Inhibitor Concentration/Enzyme Substrate Dissociation Constant)). To calculate Enzyme Substrate Modifying Factor given Enzyme Substrate Dissociation Constant, you need Inhibitor Concentration (I) & Enzyme Substrate Dissociation Constant (K_i'). With our tool, you need to enter the respective value for Inhibitor Concentration & Enzyme Substrate Dissociation Constant and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Enzyme Substrate Modifying Factor?

In this formula, Enzyme Substrate Modifying Factor uses Inhibitor Concentration & Enzyme Substrate Dissociation Constant. We can use 1 other way(s) to calculate the same, which is/are as follows -

Enzyme Substrate Modifying Factor = ((Maximum Rate*Substrate Concentration)-(Initial Reaction Rate*Michaelis Constant))/(Initial Reaction Rate*Substrate Concentration)

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