Elimination Rate Constant of Drug Solution

STEP 0: Pre-Calculation Summary
Formula Used
Elimination Rate Constant = ln(2)/Elimination Half Life
ke = ln(2)/tb/2
This formula uses 1 Functions, 2 Variables
Functions Used
ln - The natural logarithm, also known as the logarithm to the base e, is the inverse function of the natural exponential function., ln(Number)
Variables Used
Elimination Rate Constant - (Measured in 1 Per Second) - Elimination Rate Constant is the rate at which a drug is removed from the body.
Elimination Half Life - (Measured in Second) - Elimination Half Life is the time required for the concentration of the drug to reach half of its original value.
STEP 1: Convert Input(s) to Base Unit
Elimination Half Life: 12 Second --> 12 Second No Conversion Required
STEP 2: Evaluate Formula
Substituting Input Values in Formula
ke = ln(2)/tb/2 --> ln(2)/12
Evaluating ... ...
ke = 0.0577622650466621
STEP 3: Convert Result to Output's Unit
0.0577622650466621 1 Per Second -->207.944154167984 1 Per Hour (Check conversion ​here)
FINAL ANSWER
207.944154167984 207.9442 1 Per Hour <-- Elimination Rate Constant
(Calculation completed in 00.004 seconds)

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K J Somaiya College of science (K J Somaiya), Mumbai
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Elimination Rate Constant Calculators

Elimination Half Life given Volume of Plasma Cleared
​ LaTeX ​ Go Elimination Half Life = (ln(2)*Volume of Distribution)/Volume of Plasma Cleared
Elimination Rate Constant given Area under Curve
​ LaTeX ​ Go Elimination Rate Constant = Dose/(Area Under Curve*Volume of Distribution)
Elimination Rate Constant given Volume of Plasma Cleared
​ LaTeX ​ Go Elimination Rate Constant = Volume of Plasma Cleared/Volume of Distribution
Elimination Half Life of Drug
​ LaTeX ​ Go Elimination Half Life = ln(2)/Elimination Rate Constant

Elimination Rate Constant of Drug Formula

​LaTeX ​Go
Elimination Rate Constant = ln(2)/Elimination Half Life
ke = ln(2)/tb/2

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Elimination Rate Constant of Drug?

Elimination Rate Constant of Drug calculator uses Elimination Rate Constant = ln(2)/Elimination Half Life to calculate the Elimination Rate Constant, The Elimination rate constant of drug is defined as the inverse relationship with the time required for the concentration of the drug to reach half of its original value. Elimination Rate Constant is denoted by ke symbol.

How to calculate Elimination Rate Constant of Drug using this online calculator? To use this online calculator for Elimination Rate Constant of Drug, enter Elimination Half Life (tb/2) and hit the calculate button. Here is how the Elimination Rate Constant of Drug calculation can be explained with given input values -> 748599 = ln(2)/12.

FAQ

What is Elimination Rate Constant of Drug?
The Elimination rate constant of drug is defined as the inverse relationship with the time required for the concentration of the drug to reach half of its original value and is represented as ke = ln(2)/tb/2 or Elimination Rate Constant = ln(2)/Elimination Half Life. Elimination Half Life is the time required for the concentration of the drug to reach half of its original value.
How to calculate Elimination Rate Constant of Drug?
The Elimination rate constant of drug is defined as the inverse relationship with the time required for the concentration of the drug to reach half of its original value is calculated using Elimination Rate Constant = ln(2)/Elimination Half Life. To calculate Elimination Rate Constant of Drug, you need Elimination Half Life (tb/2). With our tool, you need to enter the respective value for Elimination Half Life and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
How many ways are there to calculate Elimination Rate Constant?
In this formula, Elimination Rate Constant uses Elimination Half Life. We can use 2 other way(s) to calculate the same, which is/are as follows -
  • Elimination Rate Constant = Dose/(Area Under Curve*Volume of Distribution)
  • Elimination Rate Constant = Volume of Plasma Cleared/Volume of Distribution
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