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Elimination Rate Constant given Volume of Plasma Cleared Calculator

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✖The Volume of Plasma Cleared is defined as the amount of plasma cleared of the drug per unit of time.ⓘ Volume of Plasma Cleared [CL]			+10% -10%
✖The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.ⓘ Volume of Distribution [V_d]			+10% -10%

✖Elimination Rate Constant is the rate at which a drug is removed from the body.ⓘ Elimination Rate Constant given Volume of Plasma Cleared [k_e]

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Elimination Rate Constant given Volume of Plasma Cleared Solution

STEP 0: Pre-Calculation Summary

Formula Used

Elimination Rate Constant = Volume of Plasma Cleared/Volume of Distribution
k_e = CL/V_d
This formula uses 3 Variables

Variables Used

Elimination Rate Constant - (Measured in 1 Per Second) - Elimination Rate Constant is the rate at which a drug is removed from the body.
Volume of Plasma Cleared - (Measured in Cubic Meter per Second) - The Volume of Plasma Cleared is defined as the amount of plasma cleared of the drug per unit of time.
Volume of Distribution - (Measured in Cubic Meter) - The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.

STEP 1: Convert Input(s) to Base Unit

Volume of Plasma Cleared: 0.48 Liter per Second --> 0.00048 Cubic Meter per Second (Check conversion here)
Volume of Distribution: 9 Liter --> 0.009 Cubic Meter (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

k_e = CL/V_d --> 0.00048/0.009

Evaluating ... ...

k_e = 0.0533333333333333

STEP 3: Convert Result to Output's Unit

0.0533333333333333 1 Per Second -->192 1 Per Hour (Check conversion here)

FINAL ANSWER

192 1 Per Hour <-- Elimination Rate Constant

(Calculation completed in 00.020 seconds)

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< Elimination Rate Constant Calculators

Elimination Half Life given Volume of Plasma Cleared

LaTeX Go Elimination Half Life = (ln(2)*Volume of Distribution)/Volume of Plasma Cleared

Elimination Rate Constant given Area under Curve

LaTeX Go Elimination Rate Constant = Dose/(Area Under Curve*Volume of Distribution)

Elimination Rate Constant given Volume of Plasma Cleared

LaTeX Go Elimination Rate Constant = Volume of Plasma Cleared/Volume of Distribution

Elimination Half Life of Drug

LaTeX Go Elimination Half Life = ln(2)/Elimination Rate Constant

Elimination Rate Constant given Volume of Plasma Cleared Formula

LaTeX Go

Elimination Rate Constant = Volume of Plasma Cleared/Volume of Distribution
k_e = CL/V_d

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Elimination Rate Constant given Volume of Plasma Cleared?

Elimination Rate Constant given Volume of Plasma Cleared calculator uses Elimination Rate Constant = Volume of Plasma Cleared/Volume of Distribution to calculate the Elimination Rate Constant, The Elimination rate constant given volume of plasma cleared formula is defined as the ratio of the volume of plasma cleared of the drug per unit time to the apparent volume in which a drug is distributed. Elimination Rate Constant is denoted by k_e symbol.

How to calculate Elimination Rate Constant given Volume of Plasma Cleared using this online calculator? To use this online calculator for Elimination Rate Constant given Volume of Plasma Cleared, enter Volume of Plasma Cleared (CL) & Volume of Distribution (V_d) and hit the calculate button. Here is how the Elimination Rate Constant given Volume of Plasma Cleared calculation can be explained with given input values -> 691200 = 0.00048/0.009.

FAQ

What is Elimination Rate Constant given Volume of Plasma Cleared?

The Elimination rate constant given volume of plasma cleared formula is defined as the ratio of the volume of plasma cleared of the drug per unit time to the apparent volume in which a drug is distributed and is represented as k_e = CL/V_d or Elimination Rate Constant = Volume of Plasma Cleared/Volume of Distribution. The Volume of Plasma Cleared is defined as the amount of plasma cleared of the drug per unit of time & The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.

How to calculate Elimination Rate Constant given Volume of Plasma Cleared?

The Elimination rate constant given volume of plasma cleared formula is defined as the ratio of the volume of plasma cleared of the drug per unit time to the apparent volume in which a drug is distributed is calculated using Elimination Rate Constant = Volume of Plasma Cleared/Volume of Distribution. To calculate Elimination Rate Constant given Volume of Plasma Cleared, you need Volume of Plasma Cleared (CL) & Volume of Distribution (V_d). With our tool, you need to enter the respective value for Volume of Plasma Cleared & Volume of Distribution and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Elimination Rate Constant?

In this formula, Elimination Rate Constant uses Volume of Plasma Cleared & Volume of Distribution. We can use 2 other way(s) to calculate the same, which is/are as follows -

Elimination Rate Constant = Dose/(Area Under Curve*Volume of Distribution)
Elimination Rate Constant = ln(2)/Elimination Half Life

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