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Dosing interval given average plasma concentration Calculator

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✖Area under Curve (AUC) is the definite integral of a curve that describes the variation of a drug concentration in blood plasma as a function of time.ⓘ Area Under Curve [AUC]			+10% -10%
✖Average Plasma Concentration is the average concentration of the drug after administration and before the next dose is administered.ⓘ Average Plasma Concentration [C_av]			+10% -10%

✖The Dosing Interval is the time between drug dose administrations.ⓘ Dosing interval given average plasma concentration [Τ]

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Dosing interval given average plasma concentration Solution

STEP 0: Pre-Calculation Summary

Formula Used

Dosing Interval = Area Under Curve/Average Plasma Concentration
Τ = AUC/C_av
This formula uses 3 Variables

Variables Used

Dosing Interval - (Measured in Second) - The Dosing Interval is the time between drug dose administrations.
Area Under Curve - (Measured in Mole Second per Cubic Meter) - Area under Curve (AUC) is the definite integral of a curve that describes the variation of a drug concentration in blood plasma as a function of time.
Average Plasma Concentration - (Measured in Mole per Cubic Meter) - Average Plasma Concentration is the average concentration of the drug after administration and before the next dose is administered.

STEP 1: Convert Input(s) to Base Unit

Area Under Curve: 1.32 Mole Second per Liter --> 1320 Mole Second per Cubic Meter (Check conversion here)
Average Plasma Concentration: 20 Mole per Liter --> 20000 Mole per Cubic Meter (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

Τ = AUC/C_av --> 1320/20000

Evaluating ... ...

Τ = 0.066

STEP 3: Convert Result to Output's Unit

0.066 Second --> No Conversion Required

FINAL ANSWER

0.066 Second <-- Dosing Interval

(Calculation completed in 00.004 seconds)

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Created by Prashant Singh

K J Somaiya College of science (K J Somaiya), Mumbai

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Dosing interval given average plasma concentration Formula

LaTeX Go

Dosing Interval = Area Under Curve/Average Plasma Concentration
Τ = AUC/C_av

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Dosing interval given average plasma concentration?

Dosing interval given average plasma concentration calculator uses Dosing Interval = Area Under Curve/Average Plasma Concentration to calculate the Dosing Interval, The Dosing interval given average plasma concentration formula is defined as the integral of the concentration-time curve per average plasma concentration of drugs. Dosing Interval is denoted by Τ symbol.

How to calculate Dosing interval given average plasma concentration using this online calculator? To use this online calculator for Dosing interval given average plasma concentration, enter Area Under Curve (AUC) & Average Plasma Concentration (C_av) and hit the calculate button. Here is how the Dosing interval given average plasma concentration calculation can be explained with given input values -> 0.066 = 1320/20000.

FAQ

What is Dosing interval given average plasma concentration?

The Dosing interval given average plasma concentration formula is defined as the integral of the concentration-time curve per average plasma concentration of drugs and is represented as Τ = AUC/C_av or Dosing Interval = Area Under Curve/Average Plasma Concentration. Area under Curve (AUC) is the definite integral of a curve that describes the variation of a drug concentration in blood plasma as a function of time & Average Plasma Concentration is the average concentration of the drug after administration and before the next dose is administered.

How to calculate Dosing interval given average plasma concentration?

The Dosing interval given average plasma concentration formula is defined as the integral of the concentration-time curve per average plasma concentration of drugs is calculated using Dosing Interval = Area Under Curve/Average Plasma Concentration. To calculate Dosing interval given average plasma concentration, you need Area Under Curve (AUC) & Average Plasma Concentration (C_av). With our tool, you need to enter the respective value for Area Under Curve & Average Plasma Concentration and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Dosing Interval?

In this formula, Dosing Interval uses Area Under Curve & Average Plasma Concentration. We can use 1 other way(s) to calculate the same, which is/are as follows -

Dosing Interval = (Administered Dose*Bioavailability*Drug Purity)/Drug Rate of Administration

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