Dose of drug administered intravenous Solution

STEP 0: Pre-Calculation Summary
Formula Used
Dose Intravenous = (Bioavailability of Drug*Area under Curve Intravenous*Dose Non-Intravenous)/Area under Curve Non-Intravenous
Div = (f*AUCiv*Dpo)/AUCpo
This formula uses 5 Variables
Variables Used
Dose Intravenous - (Measured in Mole) - The Dose Intravenous is the amount of drug administered intravenously.
Bioavailability of Drug - The Bioavailability of Drug is defined as the systemically available fraction of a drug.
Area under Curve Intravenous - (Measured in Mole Second per Cubic Meter) - Area under Curve Intravenous is the integral of the concentration-time curve after a single dose administered intravenous.
Dose Non-Intravenous - (Measured in Mole) - The Dose Non-Intravenous is the amount of drug administered orally.
Area under Curve Non-Intravenous - (Measured in Mole Second per Cubic Meter) - The Area under Curve Non-Intravenous is the integral of the concentration-time curve after a single dose is administered orally.
STEP 1: Convert Input(s) to Base Unit
Bioavailability of Drug: 9.5 --> No Conversion Required
Area under Curve Intravenous: 11 Mole Second per Liter --> 11000 Mole Second per Cubic Meter (Check conversion ​here)
Dose Non-Intravenous: 4 Mole --> 4 Mole No Conversion Required
Area under Curve Non-Intravenous: 6 Mole Second per Liter --> 6000 Mole Second per Cubic Meter (Check conversion ​here)
STEP 2: Evaluate Formula
Substituting Input Values in Formula
Div = (f*AUCiv*Dpo)/AUCpo --> (9.5*11000*4)/6000
Evaluating ... ...
Div = 69.6666666666667
STEP 3: Convert Result to Output's Unit
69.6666666666667 Mole --> No Conversion Required
FINAL ANSWER
69.6666666666667 69.66667 Mole <-- Dose Intravenous
(Calculation completed in 00.004 seconds)

Credits

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Created by Prashant Singh
K J Somaiya College of science (K J Somaiya), Mumbai
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University of Hawaiʻi at Mānoa (UH Manoa), Hawaii, USA
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Dose of drug administered intravenous Formula

​LaTeX ​Go
Dose Intravenous = (Bioavailability of Drug*Area under Curve Intravenous*Dose Non-Intravenous)/Area under Curve Non-Intravenous
Div = (f*AUCiv*Dpo)/AUCpo

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Dose of drug administered intravenous?

Dose of drug administered intravenous calculator uses Dose Intravenous = (Bioavailability of Drug*Area under Curve Intravenous*Dose Non-Intravenous)/Area under Curve Non-Intravenous to calculate the Dose Intravenous, The Dose of drug administered intravenous formula is defined as the comparison the bioavailability of the active drug in systemic circulation following non-intravenous administration to the bioavailability of the same drug following intravenous administration. Dose Intravenous is denoted by Div symbol.

How to calculate Dose of drug administered intravenous using this online calculator? To use this online calculator for Dose of drug administered intravenous, enter Bioavailability of Drug (f), Area under Curve Intravenous (AUCiv), Dose Non-Intravenous (Dpo) & Area under Curve Non-Intravenous (AUCpo) and hit the calculate button. Here is how the Dose of drug administered intravenous calculation can be explained with given input values -> 69.66667 = (9.5*11000*4)/6000.

FAQ

What is Dose of drug administered intravenous?
The Dose of drug administered intravenous formula is defined as the comparison the bioavailability of the active drug in systemic circulation following non-intravenous administration to the bioavailability of the same drug following intravenous administration and is represented as Div = (f*AUCiv*Dpo)/AUCpo or Dose Intravenous = (Bioavailability of Drug*Area under Curve Intravenous*Dose Non-Intravenous)/Area under Curve Non-Intravenous. The Bioavailability of Drug is defined as the systemically available fraction of a drug, Area under Curve Intravenous is the integral of the concentration-time curve after a single dose administered intravenous, The Dose Non-Intravenous is the amount of drug administered orally & The Area under Curve Non-Intravenous is the integral of the concentration-time curve after a single dose is administered orally.
How to calculate Dose of drug administered intravenous?
The Dose of drug administered intravenous formula is defined as the comparison the bioavailability of the active drug in systemic circulation following non-intravenous administration to the bioavailability of the same drug following intravenous administration is calculated using Dose Intravenous = (Bioavailability of Drug*Area under Curve Intravenous*Dose Non-Intravenous)/Area under Curve Non-Intravenous. To calculate Dose of drug administered intravenous, you need Bioavailability of Drug (f), Area under Curve Intravenous (AUCiv), Dose Non-Intravenous (Dpo) & Area under Curve Non-Intravenous (AUCpo). With our tool, you need to enter the respective value for Bioavailability of Drug, Area under Curve Intravenous, Dose Non-Intravenous & Area under Curve Non-Intravenous and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.
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