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Dose of A type drug Calculator

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✖The Area under curve Dosage A is the integral of the concentration-time curve for A form of dosage.ⓘ Area under curve Dosage A [AUC_dosageA]			+10% -10%
✖The Area under curve Dosage B is the integral of the concentration-time curve for B form of dosage.ⓘ Area under curve Dosage B [AUC_dosageB]			+10% -10%
✖Dose Type B is the amount of drug administered in B-type dosage form.ⓘ Dose Type B [D_B]			+10% -10%
✖Relative Bioavailability compares the bioavailability between two different dosage forms.ⓘ Relative Bioavailability [F_rel]			+10% -10%

✖Dose Type A is the amount of drug administered in A-type dosage form.ⓘ Dose of A type drug [D_A]

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Dose of A type drug Solution

STEP 0: Pre-Calculation Summary

Formula Used

Dose Type A = (Area under curve Dosage A/Area under curve Dosage B)*(Dose Type B/Relative Bioavailability)
D_A = (AUC_dosageA/AUC_dosageB)*(D_B/F_rel)
This formula uses 5 Variables

Variables Used

Dose Type A - (Measured in Mole) - Dose Type A is the amount of drug administered in A-type dosage form.
Area under curve Dosage A - (Measured in Mole Second per Cubic Meter) - The Area under curve Dosage A is the integral of the concentration-time curve for A form of dosage.
Area under curve Dosage B - (Measured in Mole Second per Cubic Meter) - The Area under curve Dosage B is the integral of the concentration-time curve for B form of dosage.
Dose Type B - (Measured in Mole) - Dose Type B is the amount of drug administered in B-type dosage form.
Relative Bioavailability - Relative Bioavailability compares the bioavailability between two different dosage forms.

STEP 1: Convert Input(s) to Base Unit

Area under curve Dosage A: 1.141 Mole Second per Liter --> 1141 Mole Second per Cubic Meter (Check conversion here)
Area under curve Dosage B: 1.732 Mole Second per Liter --> 1732 Mole Second per Cubic Meter (Check conversion here)
Dose Type B: 15 Mole --> 15 Mole No Conversion Required
Relative Bioavailability: 0.9 --> No Conversion Required

STEP 2: Evaluate Formula

Substituting Input Values in Formula

D_A = (AUC_dosageA/AUC_dosageB)*(D_B/F_rel) --> (1141/1732)*(15/0.9)

Evaluating ... ...

D_A = 10.9795996920708

STEP 3: Convert Result to Output's Unit

10.9795996920708 Mole --> No Conversion Required

FINAL ANSWER

10.9795996920708 ≈ 10.9796 Mole <-- Dose Type A

(Calculation completed in 00.004 seconds)

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Created by Prashant Singh

K J Somaiya College of science (K J Somaiya), Mumbai

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Dose of A type drug Formula

LaTeX Go

Dose Type A = (Area under curve Dosage A/Area under curve Dosage B)*(Dose Type B/Relative Bioavailability)
D_A = (AUC_dosageA/AUC_dosageB)*(D_B/F_rel)

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Dose of A type drug?

Dose of A type drug calculator uses Dose Type A = (Area under curve Dosage A/Area under curve Dosage B)*(Dose Type B/Relative Bioavailability) to calculate the Dose Type A, The Dose of A type drug formula is defined as the comparison of the bioavailability between two different dosage forms. The relative AUCs are used to make this comparison and relative doses are used to normalize the calculation. Dose Type A is denoted by D_A symbol.

How to calculate Dose of A type drug using this online calculator? To use this online calculator for Dose of A type drug, enter Area under curve Dosage A (AUC_dosageA), Area under curve Dosage B (AUC_dosageB), Dose Type B (D_B) & Relative Bioavailability (F_rel) and hit the calculate button. Here is how the Dose of A type drug calculation can be explained with given input values -> 10.9796 = (1141/1732)*(15/0.9).

FAQ

What is Dose of A type drug?

The Dose of A type drug formula is defined as the comparison of the bioavailability between two different dosage forms. The relative AUCs are used to make this comparison and relative doses are used to normalize the calculation and is represented as D_A = (AUC_dosageA/AUC_dosageB)*(D_B/F_rel) or Dose Type A = (Area under curve Dosage A/Area under curve Dosage B)*(Dose Type B/Relative Bioavailability). The Area under curve Dosage A is the integral of the concentration-time curve for A form of dosage, The Area under curve Dosage B is the integral of the concentration-time curve for B form of dosage, Dose Type B is the amount of drug administered in B-type dosage form & Relative Bioavailability compares the bioavailability between two different dosage forms.

How to calculate Dose of A type drug?

The Dose of A type drug formula is defined as the comparison of the bioavailability between two different dosage forms. The relative AUCs are used to make this comparison and relative doses are used to normalize the calculation is calculated using Dose Type A = (Area under curve Dosage A/Area under curve Dosage B)*(Dose Type B/Relative Bioavailability). To calculate Dose of A type drug, you need Area under curve Dosage A (AUC_dosageA), Area under curve Dosage B (AUC_dosageB), Dose Type B (D_B) & Relative Bioavailability (F_rel). With our tool, you need to enter the respective value for Area under curve Dosage A, Area under curve Dosage B, Dose Type B & Relative Bioavailability and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

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