Dissociation Rate Constant given Catalytic Rate Constant Calculator

✖The Catalytic Rate Constant is defined as the rate constant for conversion of the enzyme-substrate complex to enzyme and product.ⓘ Catalytic Rate Constant [k_cat]			+10% -10%
✖The Initial Enzyme Concentration is defined as the concentration of enzyme at the start of the reaction.ⓘ Initial Enzyme Concentration [[E₀]]			+10% -10%
✖The Substrate Concentration is the number of moles of substrate per liter solution.ⓘ Substrate Concentration [S]			+10% -10%
✖The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.ⓘ Initial Reaction Rate [V₀]			+10% -10%

✖The Dissociation Rate Constant is the ratio of reverse and forward rate constant.ⓘ Dissociation Rate Constant given Catalytic Rate Constant [K_D]

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Dissociation Rate Constant given Catalytic Rate Constant Solution

STEP 0: Pre-Calculation Summary

Formula Used

Dissociation Rate Constant = ((Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration
K_D = ((k_cat*[E₀]*S)/V₀)-S
This formula uses 5 Variables

Variables Used

Dissociation Rate Constant - (Measured in Mole per Cubic Meter) - The Dissociation Rate Constant is the ratio of reverse and forward rate constant.
Catalytic Rate Constant - (Measured in 1 Per Second) - The Catalytic Rate Constant is defined as the rate constant for conversion of the enzyme-substrate complex to enzyme and product.
Initial Enzyme Concentration - (Measured in Mole per Cubic Meter) - The Initial Enzyme Concentration is defined as the concentration of enzyme at the start of the reaction.
Substrate Concentration - (Measured in Mole per Cubic Meter) - The Substrate Concentration is the number of moles of substrate per liter solution.
Initial Reaction Rate - (Measured in Mole per Cubic Meter Second) - The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.

STEP 1: Convert Input(s) to Base Unit

Catalytic Rate Constant: 0.65 1 Per Second --> 0.65 1 Per Second No Conversion Required
Initial Enzyme Concentration: 100 Mole per Liter --> 100000 Mole per Cubic Meter (Check conversion here)
Substrate Concentration: 1.5 Mole per Liter --> 1500 Mole per Cubic Meter (Check conversion here)
Initial Reaction Rate: 0.45 Mole per Liter Second --> 450 Mole per Cubic Meter Second (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

K_D = ((k_cat*[E₀]*S)/V₀)-S --> ((0.65*100000*1500)/450)-1500

Evaluating ... ...

K_D = 215166.666666667

STEP 3: Convert Result to Output's Unit

215166.666666667 Mole per Cubic Meter -->215.166666666667 Mole per Liter (Check conversion here)

FINAL ANSWER

215.166666666667 ≈ 215.1667 Mole per Liter <-- Dissociation Rate Constant

(Calculation completed in 00.020 seconds)

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< Rate Constants of Enzymatic Reaction Calculators

Forward Rate Constant in Enzymatic Reaction mechanism

LaTeX Go Forward Rate Constant = (Reverse Rate Constant*Enzyme Substrate Complex Concentration)/(Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))

Reverse Rate Constant in Enzymatic Reaction Mechanism

LaTeX Go Reverse Rate Constant = (Forward Rate Constant*Substrate Concentration*(Initial Enzyme Concentration-Enzyme Substrate Complex Concentration))/Enzyme Substrate Complex Concentration

Catalytic Rate Constant at Low Substrate Concentration

LaTeX Go Catalytic Rate Constant = (Initial Reaction Rate*Michaelis Constant)/(Initial Enzyme Concentration*Substrate Concentration)

Dissociation Rate Constant in Enzymatic Reaction Mechanism

LaTeX Go Dissociation Rate Constant = Reverse Rate Constant/Forward Rate Constant

Dissociation Rate Constant given Catalytic Rate Constant Formula

LaTeX Go

Dissociation Rate Constant = ((Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration
K_D = ((k_cat*[E₀]*S)/V₀)-S

What is Michaelis–Menten kinetics model?

In biochemistry, Michaelis–Menten kinetics is one of the best-known models of enzyme kinetics. Biochemical reactions involving a single substrate are often assumed to follow Michaelis–Menten kinetics, without regard to the model's underlying assumptions. The model takes the form of an equation describing the rate of enzymatic reactions, by relating the reaction rate of formation of product to the concentration of a substrate.

How to Calculate Dissociation Rate Constant given Catalytic Rate Constant?

Dissociation Rate Constant given Catalytic Rate Constant calculator uses Dissociation Rate Constant = ((Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration to calculate the Dissociation Rate Constant, The Dissociation rate constant given catalytic rate constant formula is defined as the relation with an initial rate of the system, catalytic rate constant, and with enzyme and substrate concentration. Dissociation Rate Constant is denoted by K_D symbol.

How to calculate Dissociation Rate Constant given Catalytic Rate Constant using this online calculator? To use this online calculator for Dissociation Rate Constant given Catalytic Rate Constant, enter Catalytic Rate Constant (k_cat), Initial Enzyme Concentration ([E₀]), Substrate Concentration (S) & Initial Reaction Rate (V₀) and hit the calculate button. Here is how the Dissociation Rate Constant given Catalytic Rate Constant calculation can be explained with given input values -> 0.215167 = ((0.65*100000*1500)/450)-1500.

FAQ

What is Dissociation Rate Constant given Catalytic Rate Constant?

The Dissociation rate constant given catalytic rate constant formula is defined as the relation with an initial rate of the system, catalytic rate constant, and with enzyme and substrate concentration and is represented as K_D = ((k_cat*[E₀]*S)/V₀)-S or Dissociation Rate Constant = ((Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration. The Catalytic Rate Constant is defined as the rate constant for conversion of the enzyme-substrate complex to enzyme and product, The Initial Enzyme Concentration is defined as the concentration of enzyme at the start of the reaction, The Substrate Concentration is the number of moles of substrate per liter solution & The Initial Reaction Rate is defined as the initial speed at which a chemical reaction takes place.

How to calculate Dissociation Rate Constant given Catalytic Rate Constant?

The Dissociation rate constant given catalytic rate constant formula is defined as the relation with an initial rate of the system, catalytic rate constant, and with enzyme and substrate concentration is calculated using Dissociation Rate Constant = ((Catalytic Rate Constant*Initial Enzyme Concentration*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration. To calculate Dissociation Rate Constant given Catalytic Rate Constant, you need Catalytic Rate Constant (k_cat), Initial Enzyme Concentration ([E₀]), Substrate Concentration (S) & Initial Reaction Rate (V₀). With our tool, you need to enter the respective value for Catalytic Rate Constant, Initial Enzyme Concentration, Substrate Concentration & Initial Reaction Rate and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Dissociation Rate Constant?

In this formula, Dissociation Rate Constant uses Catalytic Rate Constant, Initial Enzyme Concentration, Substrate Concentration & Initial Reaction Rate. We can use 2 other way(s) to calculate the same, which is/are as follows -

Dissociation Rate Constant = Reverse Rate Constant/Forward Rate Constant
Dissociation Rate Constant = ((Maximum Rate*Substrate Concentration)/Initial Reaction Rate)-Substrate Concentration

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