Dissociation Constant of Enzyme Substrate Complex given Modifying Factor of Enzyme Substrate Calculator

✖The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.ⓘ Inhibitor Concentration [I]			+10% -10%
✖The Enzyme Substrate Modifying Factor is defined by the inhibitor concentration and the dissociation constant of the enzyme-substrate complex.ⓘ Enzyme Substrate Modifying Factor [α^']			+10% -10%

✖The Enzyme Substrate Dissociation Constant is difficult to measure directly since the enzyme-substrate complex is short-lived and undergoes a chemical reaction to form the product.ⓘ Dissociation Constant of Enzyme Substrate Complex given Modifying Factor of Enzyme Substrate [K_i']

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Dissociation Constant of Enzyme Substrate Complex given Modifying Factor of Enzyme Substrate Solution

STEP 0: Pre-Calculation Summary

Formula Used

Enzyme Substrate Dissociation Constant = Inhibitor Concentration/(Enzyme Substrate Modifying Factor-1)
K_i' = I/(α^'-1)
This formula uses 3 Variables

Variables Used

Enzyme Substrate Dissociation Constant - (Measured in Mole per Cubic Meter) - The Enzyme Substrate Dissociation Constant is difficult to measure directly since the enzyme-substrate complex is short-lived and undergoes a chemical reaction to form the product.
Inhibitor Concentration - (Measured in Mole per Cubic Meter) - The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system.
Enzyme Substrate Modifying Factor - The Enzyme Substrate Modifying Factor is defined by the inhibitor concentration and the dissociation constant of the enzyme-substrate complex.

STEP 1: Convert Input(s) to Base Unit

Inhibitor Concentration: 9 Mole per Liter --> 9000 Mole per Cubic Meter (Check conversion here)
Enzyme Substrate Modifying Factor: 2 --> No Conversion Required

STEP 2: Evaluate Formula

Substituting Input Values in Formula

K_i' = I/(α^'-1) --> 9000/(2-1)

Evaluating ... ...

K_i' = 9000

STEP 3: Convert Result to Output's Unit

9000 Mole per Cubic Meter -->9 Mole per Liter (Check conversion here)

FINAL ANSWER

9 Mole per Liter <-- Enzyme Substrate Dissociation Constant

(Calculation completed in 00.005 seconds)

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< Competitive Inhibitor Calculators

Substrate Concentration of Competitive Inhibition of Enzyme Catalysis

LaTeX Go Substrate Concentration = (Initial Reaction Rate*(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))))/((Final Rate Constant*Initial Enzyme Concentration)-Initial Reaction Rate)

Substrate Concentration in Competitive Inhibition given Enzyme Substrate Complex Concentration

LaTeX Go Substrate Concentration = (Enzyme Substrate Complex Concentration*(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))))/((Initial Enzyme Concentration)-Enzyme Substrate Complex Concentration)

Substrate Concentration in Competitive Inhibition given Maximum Rate of System

LaTeX Go Substrate Concentration = (Initial Reaction Rate*(Michaelis Constant*(1+(Inhibitor Concentration/Enzyme Inhibitor Dissociation Constant))))/(Maximum Rate-Initial Reaction Rate)

Apparent Value of Michaelis Menten Constant in Presence of Competitive Inhibition

LaTeX Go Apparent Michaelis Constant = (Substrate Concentration*(Maximum Rate-Initial Reaction Rate))/Initial Reaction Rate

Dissociation Constant of Enzyme Substrate Complex given Modifying Factor of Enzyme Substrate Formula

LaTeX Go

Enzyme Substrate Dissociation Constant = Inhibitor Concentration/(Enzyme Substrate Modifying Factor-1)
K_i' = I/(α^'-1)

What is competitive Inhibition?

In competitive inhibition, the substrate and inhibitor cannot bind to the enzyme at the same time,this usually results from the inhibitor having an affinity for the active site of an enzyme where the substrate also binds; the substrate and inhibitor compete for access to the enzyme's active site.This type of inhibition can overcome by sufficiently high concentrations of substrate (Vmax remains constant), i.e., by out-competing the inhibitor. However, the apparent Km will increase as it takes a higher concentration of the substrate to reach the Km point, or half the Vmax. Competitive inhibitors are often similar in structure to the real substrate.

How to Calculate Dissociation Constant of Enzyme Substrate Complex given Modifying Factor of Enzyme Substrate?

Dissociation Constant of Enzyme Substrate Complex given Modifying Factor of Enzyme Substrate calculator uses Enzyme Substrate Dissociation Constant = Inhibitor Concentration/(Enzyme Substrate Modifying Factor-1) to calculate the Enzyme Substrate Dissociation Constant, The Dissociation constant of enzyme substrate complex given modifying factor of enzyme substrate formula is defined as the relation with inhibitor concentration and with the modifying factor of enzyme-substrate complex of the system. Enzyme Substrate Dissociation Constant is denoted by K_i' symbol.

How to calculate Dissociation Constant of Enzyme Substrate Complex given Modifying Factor of Enzyme Substrate using this online calculator? To use this online calculator for Dissociation Constant of Enzyme Substrate Complex given Modifying Factor of Enzyme Substrate, enter Inhibitor Concentration (I) & Enzyme Substrate Modifying Factor (α^') and hit the calculate button. Here is how the Dissociation Constant of Enzyme Substrate Complex given Modifying Factor of Enzyme Substrate calculation can be explained with given input values -> 0.009 = 9000/(2-1).

FAQ

What is Dissociation Constant of Enzyme Substrate Complex given Modifying Factor of Enzyme Substrate?

The Dissociation constant of enzyme substrate complex given modifying factor of enzyme substrate formula is defined as the relation with inhibitor concentration and with the modifying factor of enzyme-substrate complex of the system and is represented as K_i' = I/(α^'-1) or Enzyme Substrate Dissociation Constant = Inhibitor Concentration/(Enzyme Substrate Modifying Factor-1). The Inhibitor concentration is defined as the number of moles of inhibitor present per liter of solution of the system & The Enzyme Substrate Modifying Factor is defined by the inhibitor concentration and the dissociation constant of the enzyme-substrate complex.

How to calculate Dissociation Constant of Enzyme Substrate Complex given Modifying Factor of Enzyme Substrate?

The Dissociation constant of enzyme substrate complex given modifying factor of enzyme substrate formula is defined as the relation with inhibitor concentration and with the modifying factor of enzyme-substrate complex of the system is calculated using Enzyme Substrate Dissociation Constant = Inhibitor Concentration/(Enzyme Substrate Modifying Factor-1). To calculate Dissociation Constant of Enzyme Substrate Complex given Modifying Factor of Enzyme Substrate, you need Inhibitor Concentration (I) & Enzyme Substrate Modifying Factor (α^'). With our tool, you need to enter the respective value for Inhibitor Concentration & Enzyme Substrate Modifying Factor and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

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