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Concentration of Drug using Volume of Distribution Calculator

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✖The Dose is the amount of drug administered.ⓘ Dose [D]			+10% -10%
✖The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.ⓘ Volume of Distribution [V_d]			+10% -10%

✖Concentration of Drug is the amount of the drug in a given volume of plasma.ⓘ Concentration of Drug using Volume of Distribution [C_ss]

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Concentration of Drug using Volume of Distribution Solution

STEP 0: Pre-Calculation Summary

Formula Used

Concentration of Drug = Dose/Volume of Distribution
C_ss = D/V_d
This formula uses 3 Variables

Variables Used

Concentration of Drug - (Measured in Mole per Cubic Meter) - Concentration of Drug is the amount of the drug in a given volume of plasma.
Dose - (Measured in Mole) - The Dose is the amount of drug administered.
Volume of Distribution - (Measured in Cubic Meter) - The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.

STEP 1: Convert Input(s) to Base Unit

Dose: 8 Mole --> 8 Mole No Conversion Required
Volume of Distribution: 9 Liter --> 0.009 Cubic Meter (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

C_ss = D/V_d --> 8/0.009

Evaluating ... ...

C_ss = 888.888888888889

STEP 3: Convert Result to Output's Unit

888.888888888889 Mole per Cubic Meter -->0.888888888888889 Mole per Liter (Check conversion here)

FINAL ANSWER

0.888888888888889 ≈ 0.888889 Mole per Liter <-- Concentration of Drug

(Calculation completed in 00.020 seconds)

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Created by Ritacheta Sen

University of Calcutta (C.U), Kolkata

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< Drug Content Calculators

Rate of Infusion of Drug

LaTeX Go Rate of Infusion = Volume of Plasma Cleared*Concentration of Drug

Absorption Half-Life of Drug

LaTeX Go Absorption Half Life = ln(2)/Absorption Rate Constant

Drug Rate Entering Body

LaTeX Go Absorption Rate Constant = ln(2)/Absorption Half Life

Apparent Volume of Drug Distribution

LaTeX Go Volume of Distribution = Dose/Concentration of Drug

Concentration of Drug using Volume of Distribution Formula

LaTeX Go

Concentration of Drug = Dose/Volume of Distribution
C_ss = D/V_d

What is the main application of pharmacokinetics ?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Concentration of Drug using Volume of Distribution?

Concentration of Drug using Volume of Distribution calculator uses Concentration of Drug = Dose/Volume of Distribution to calculate the Concentration of Drug, The Concentration of Drug Using Volume of Distribution formula is defined as the ratio of the amount of drug administered to the apparent volume of drug distribution. Concentration of Drug is denoted by C_ss symbol.

How to calculate Concentration of Drug using Volume of Distribution using this online calculator? To use this online calculator for Concentration of Drug using Volume of Distribution, enter Dose (D) & Volume of Distribution (V_d) and hit the calculate button. Here is how the Concentration of Drug using Volume of Distribution calculation can be explained with given input values -> 0.000889 = 8/0.009.

FAQ

What is Concentration of Drug using Volume of Distribution?

The Concentration of Drug Using Volume of Distribution formula is defined as the ratio of the amount of drug administered to the apparent volume of drug distribution and is represented as C_ss = D/V_d or Concentration of Drug = Dose/Volume of Distribution. The Dose is the amount of drug administered & The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.

How to calculate Concentration of Drug using Volume of Distribution?

The Concentration of Drug Using Volume of Distribution formula is defined as the ratio of the amount of drug administered to the apparent volume of drug distribution is calculated using Concentration of Drug = Dose/Volume of Distribution. To calculate Concentration of Drug using Volume of Distribution, you need Dose (D) & Volume of Distribution (V_d). With our tool, you need to enter the respective value for Dose & Volume of Distribution and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Concentration of Drug?

In this formula, Concentration of Drug uses Dose & Volume of Distribution. We can use 1 other way(s) to calculate the same, which is/are as follows -

Concentration of Drug = Rate of Infusion/Volume of Plasma Cleared

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