What is Pharmacokinetics?
Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.
How to Calculate Bioavailability of Drug?
Bioavailability of Drug calculator uses Bioavailability of Drug = (Area under Curve Non-Intravenous*Dose Intravenous)/(Area under Curve Intravenous*Dose Non-Intravenous) to calculate the Bioavailability of Drug, The Bioavailability of drug formula is defined as the comparison the bioavailability of the active drug in systemic circulation following non-intravenous administration to the bioavailability of the same drug following intravenous administration. Bioavailability of Drug is denoted by f symbol.
How to calculate Bioavailability of Drug using this online calculator? To use this online calculator for Bioavailability of Drug, enter Area under Curve Non-Intravenous (AUCpo), Dose Intravenous (Div), Area under Curve Intravenous (AUCiv) & Dose Non-Intravenous (Dpo) and hit the calculate button. Here is how the Bioavailability of Drug calculation can be explained with given input values -> 1.636364 = (6000*12)/(11000*4).