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Bioavailability given Rate of Administration and Dosing Interval Calculator

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✖Drug Rate of Administration is the amount of drug administered in a particular interval of time.ⓘ Drug Rate of Administration [V_a]			+10% -10%
✖The Dosing Interval is the time between drug dose administrations.ⓘ Dosing Interval [Τ]			+10% -10%
✖Administered Dose is the amount of drug administered for a pharmacological response.ⓘ Administered Dose [D_a]			+10% -10%
✖The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present.ⓘ Drug Purity [Q]			+10% -10%

✖The Bioavailability is the systemically available fraction of a drug.ⓘ Bioavailability given Rate of Administration and Dosing Interval [B]

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Bioavailability given Rate of Administration and Dosing Interval Solution

STEP 0: Pre-Calculation Summary

Formula Used

Bioavailability = (Drug Rate of Administration*Dosing Interval)/(Administered Dose*Drug Purity)
B = (V_a*Τ)/(D_a*Q)
This formula uses 5 Variables

Variables Used

Bioavailability - The Bioavailability is the systemically available fraction of a drug.
Drug Rate of Administration - (Measured in Kilogram per Second) - Drug Rate of Administration is the amount of drug administered in a particular interval of time.
Dosing Interval - (Measured in Second) - The Dosing Interval is the time between drug dose administrations.
Administered Dose - (Measured in Kilogram) - Administered Dose is the amount of drug administered for a pharmacological response.
Drug Purity - The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present.

STEP 1: Convert Input(s) to Base Unit

Drug Rate of Administration: 45 Milligram per Second --> 4.5E-05 Kilogram per Second (Check conversion here)
Dosing Interval: 44 Second --> 44 Second No Conversion Required
Administered Dose: 3.5 Microgram --> 3.5E-09 Kilogram (Check conversion here)
Drug Purity: 69 --> No Conversion Required

STEP 2: Evaluate Formula

Substituting Input Values in Formula

B = (V_a*Τ)/(D_a*Q) --> (4.5E-05*44)/(3.5E-09*69)

Evaluating ... ...

B = 8198.75776397516

STEP 3: Convert Result to Output's Unit

8198.75776397516 --> No Conversion Required

FINAL ANSWER

8198.75776397516 ≈ 8198.758 <-- Bioavailability

(Calculation completed in 00.004 seconds)

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< Bioavailability Calculators

Bioavailability of Drug

LaTeX Go Bioavailability of Drug = (Area under Curve Non-Intravenous*Dose Intravenous)/(Area under Curve Intravenous*Dose Non-Intravenous)

Bioavailability given Rate of Administration and Dosing Interval

LaTeX Go Bioavailability = (Drug Rate of Administration*Dosing Interval)/(Administered Dose*Drug Purity)

Bioavailability given Drug Purity

LaTeX Go Bioavailability = Effective Dose/(Drug Purity*Administered Dose)

Bioavailability given Effective and Administrative Dose

LaTeX Go Bioavailability = Effective Dose/Administered Dose

Bioavailability given Rate of Administration and Dosing Interval Formula

LaTeX Go

Bioavailability = (Drug Rate of Administration*Dosing Interval)/(Administered Dose*Drug Purity)
B = (V_a*Τ)/(D_a*Q)

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Bioavailability given Rate of Administration and Dosing Interval?

Bioavailability given Rate of Administration and Dosing Interval calculator uses Bioavailability = (Drug Rate of Administration*Dosing Interval)/(Administered Dose*Drug Purity) to calculate the Bioavailability, The Bioavailability given rate of administration and dosing interval formula is defined as the relation with the rate of administration of drug and dosing interval. Bioavailability is denoted by B symbol.

How to calculate Bioavailability given Rate of Administration and Dosing Interval using this online calculator? To use this online calculator for Bioavailability given Rate of Administration and Dosing Interval, enter Drug Rate of Administration (V_a), Dosing Interval (Τ), Administered Dose (D_a) & Drug Purity (Q) and hit the calculate button. Here is how the Bioavailability given Rate of Administration and Dosing Interval calculation can be explained with given input values -> 8198.758 = (4.5E-05*44)/(3.5E-09*69).

FAQ

What is Bioavailability given Rate of Administration and Dosing Interval?

The Bioavailability given rate of administration and dosing interval formula is defined as the relation with the rate of administration of drug and dosing interval and is represented as B = (V_a*Τ)/(D_a*Q) or Bioavailability = (Drug Rate of Administration*Dosing Interval)/(Administered Dose*Drug Purity). Drug Rate of Administration is the amount of drug administered in a particular interval of time, The Dosing Interval is the time between drug dose administrations, Administered Dose is the amount of drug administered for a pharmacological response & The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present.

How to calculate Bioavailability given Rate of Administration and Dosing Interval?

The Bioavailability given rate of administration and dosing interval formula is defined as the relation with the rate of administration of drug and dosing interval is calculated using Bioavailability = (Drug Rate of Administration*Dosing Interval)/(Administered Dose*Drug Purity). To calculate Bioavailability given Rate of Administration and Dosing Interval, you need Drug Rate of Administration (V_a), Dosing Interval (Τ), Administered Dose (D_a) & Drug Purity (Q). With our tool, you need to enter the respective value for Drug Rate of Administration, Dosing Interval, Administered Dose & Drug Purity and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Bioavailability?

In this formula, Bioavailability uses Drug Rate of Administration, Dosing Interval, Administered Dose & Drug Purity. We can use 2 other way(s) to calculate the same, which is/are as follows -

Bioavailability = Effective Dose/Administered Dose
Bioavailability = Effective Dose/(Drug Purity*Administered Dose)

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