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Apparent Volume of Drug Distribution Calculator

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✖The Dose is the amount of drug administered.ⓘ Dose [D]			+10% -10%
✖Concentration of Drug is the amount of the drug in a given volume of plasma.ⓘ Concentration of Drug [C_ss]			+10% -10%

✖The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.ⓘ Apparent Volume of Drug Distribution [V_d]

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Apparent Volume of Drug Distribution Solution

STEP 0: Pre-Calculation Summary

Formula Used

Volume of Distribution = Dose/Concentration of Drug
V_d = D/C_ss
This formula uses 3 Variables

Variables Used

Volume of Distribution - (Measured in Cubic Meter) - The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.
Dose - (Measured in Mole) - The Dose is the amount of drug administered.
Concentration of Drug - (Measured in Mole per Cubic Meter) - Concentration of Drug is the amount of the drug in a given volume of plasma.

STEP 1: Convert Input(s) to Base Unit

Dose: 8 Mole --> 8 Mole No Conversion Required
Concentration of Drug: 83.3 Mole per Liter --> 83300 Mole per Cubic Meter (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

V_d = D/C_ss --> 8/83300

Evaluating ... ...

V_d = 9.60384153661465E-05

STEP 3: Convert Result to Output's Unit

9.60384153661465E-05 Cubic Meter -->0.0960384153661465 Liter (Check conversion here)

FINAL ANSWER

0.0960384153661465 ≈ 0.096038 Liter <-- Volume of Distribution

(Calculation completed in 00.004 seconds)

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Created by Prashant Singh

K J Somaiya College of science (K J Somaiya), Mumbai

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< Drug Content Calculators

Rate of Infusion of Drug

LaTeX Go Rate of Infusion = Volume of Plasma Cleared*Concentration of Drug

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LaTeX Go Absorption Half Life = ln(2)/Absorption Rate Constant

Drug Rate Entering Body

LaTeX Go Absorption Rate Constant = ln(2)/Absorption Half Life

Apparent Volume of Drug Distribution

LaTeX Go Volume of Distribution = Dose/Concentration of Drug

Apparent Volume of Drug Distribution Formula

LaTeX Go

Volume of Distribution = Dose/Concentration of Drug
V_d = D/C_ss

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Apparent Volume of Drug Distribution?

Apparent Volume of Drug Distribution calculator uses Volume of Distribution = Dose/Concentration of Drug to calculate the Volume of Distribution, The Apparent volume of drug distribution formula is defined as the ratio of amount of drug administered to the concentration of drug. Volume of Distribution is denoted by V_d symbol.

How to calculate Apparent Volume of Drug Distribution using this online calculator? To use this online calculator for Apparent Volume of Drug Distribution, enter Dose (D) & Concentration of Drug (C_ss) and hit the calculate button. Here is how the Apparent Volume of Drug Distribution calculation can be explained with given input values -> 96.03842 = 8/83300.

FAQ

What is Apparent Volume of Drug Distribution?

The Apparent volume of drug distribution formula is defined as the ratio of amount of drug administered to the concentration of drug and is represented as V_d = D/C_ss or Volume of Distribution = Dose/Concentration of Drug. The Dose is the amount of drug administered & Concentration of Drug is the amount of the drug in a given volume of plasma.

How to calculate Apparent Volume of Drug Distribution?

The Apparent volume of drug distribution formula is defined as the ratio of amount of drug administered to the concentration of drug is calculated using Volume of Distribution = Dose/Concentration of Drug. To calculate Apparent Volume of Drug Distribution, you need Dose (D) & Concentration of Drug (C_ss). With our tool, you need to enter the respective value for Dose & Concentration of Drug and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

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