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Amount of drug in given volume of plasma Calculator

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✖The Dose is the amount of drug administered.ⓘ Dose [D]			+10% -10%
✖The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.ⓘ Volume of Distribution [V_dis]			+10% -10%

✖Concentration of Drug is the amount of the drug in a given volume of plasma.ⓘ Amount of drug in given volume of plasma [C_ss]

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Amount of drug in given volume of plasma Solution

STEP 0: Pre-Calculation Summary

Formula Used

Concentration of Drug = Dose/Volume of Distribution
C_ss = D/V_dis
This formula uses 3 Variables

Variables Used

Concentration of Drug - (Measured in Mole per Cubic Meter) - Concentration of Drug is the amount of the drug in a given volume of plasma.
Dose - (Measured in Mole) - The Dose is the amount of drug administered.
Volume of Distribution - (Measured in Cubic Meter) - The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.

STEP 1: Convert Input(s) to Base Unit

Dose: 8 Mole --> 8 Mole No Conversion Required
Volume of Distribution: 9 Liter --> 0.009 Cubic Meter (Check conversion here)

STEP 2: Evaluate Formula

Substituting Input Values in Formula

C_ss = D/V_dis --> 8/0.009

Evaluating ... ...

C_ss = 888.888888888889

STEP 3: Convert Result to Output's Unit

888.888888888889 Mole per Cubic Meter -->0.888888888888889 Mole per Liter (Check conversion here)

FINAL ANSWER

0.888888888888889 ≈ 0.888889 Mole per Liter <-- Concentration of Drug

(Calculation completed in 00.004 seconds)

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Created by Prashant Singh

K J Somaiya College of science (K J Somaiya), Mumbai

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Amount of drug in given volume of plasma Formula

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Concentration of Drug = Dose/Volume of Distribution
C_ss = D/V_dis

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Amount of drug in given volume of plasma?

Amount of drug in given volume of plasma calculator uses Concentration of Drug = Dose/Volume of Distribution to calculate the Concentration of Drug, Amount of drug in given volume of plasma formula is defined as ratio of amount of drug administered to apparent volume of drug. Concentration of Drug is denoted by C_ss symbol.

How to calculate Amount of drug in given volume of plasma using this online calculator? To use this online calculator for Amount of drug in given volume of plasma, enter Dose (D) & Volume of Distribution (V_dis) and hit the calculate button. Here is how the Amount of drug in given volume of plasma calculation can be explained with given input values -> 0.000889 = 8/0.009.

FAQ

What is Amount of drug in given volume of plasma?

Amount of drug in given volume of plasma formula is defined as ratio of amount of drug administered to apparent volume of drug and is represented as C_ss = D/V_dis or Concentration of Drug = Dose/Volume of Distribution. The Dose is the amount of drug administered & The Volume of Distribution is the parameter relating drug concentration in plasma to drug amount in the body.

How to calculate Amount of drug in given volume of plasma?

Amount of drug in given volume of plasma formula is defined as ratio of amount of drug administered to apparent volume of drug is calculated using Concentration of Drug = Dose/Volume of Distribution. To calculate Amount of drug in given volume of plasma, you need Dose (D) & Volume of Distribution (V_dis). With our tool, you need to enter the respective value for Dose & Volume of Distribution and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

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