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Administrative dose given rate of administration and dosing interval Calculator

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✖Drug Rate of Administration is the amount of drug administered in a particular interval of time.ⓘ Drug Rate of Administration [V_a]			+10% -10%
✖The Dosing Interval is the time between drug dose administrations.ⓘ Dosing Interval [Τ]			+10% -10%
✖The Bioavailability is the systemically available fraction of a drug.ⓘ Bioavailability [B]			+10% -10%
✖The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present.ⓘ Drug Purity [Q]			+10% -10%

✖Administered Dose is the amount of drug administered for a pharmacological response.ⓘ Administrative dose given rate of administration and dosing interval [D_a]

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Administrative dose given rate of administration and dosing interval Solution

STEP 0: Pre-Calculation Summary

Formula Used

Administered Dose = (Drug Rate of Administration*Dosing Interval)/(Bioavailability*Drug Purity)
D_a = (V_a*Τ)/(B*Q)
This formula uses 5 Variables

Variables Used

Administered Dose - (Measured in Kilogram) - Administered Dose is the amount of drug administered for a pharmacological response.
Drug Rate of Administration - (Measured in Kilogram per Second) - Drug Rate of Administration is the amount of drug administered in a particular interval of time.
Dosing Interval - (Measured in Second) - The Dosing Interval is the time between drug dose administrations.
Bioavailability - The Bioavailability is the systemically available fraction of a drug.
Drug Purity - The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present.

STEP 1: Convert Input(s) to Base Unit

Drug Rate of Administration: 45 Milligram per Second --> 4.5E-05 Kilogram per Second (Check conversion here)
Dosing Interval: 44 Second --> 44 Second No Conversion Required
Bioavailability: 12.5 --> No Conversion Required
Drug Purity: 69 --> No Conversion Required

STEP 2: Evaluate Formula

Substituting Input Values in Formula

D_a = (V_a*Τ)/(B*Q) --> (4.5E-05*44)/(12.5*69)

Evaluating ... ...

D_a = 2.29565217391304E-06

STEP 3: Convert Result to Output's Unit

2.29565217391304E-06 Kilogram -->2295.65217391304 Microgram (Check conversion here)

FINAL ANSWER

2295.65217391304 ≈ 2295.652 Microgram <-- Administered Dose

(Calculation completed in 00.020 seconds)

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Administrative dose given rate of administration and dosing interval Formula

LaTeX Go

Administered Dose = (Drug Rate of Administration*Dosing Interval)/(Bioavailability*Drug Purity)
D_a = (V_a*Τ)/(B*Q)

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Administrative dose given rate of administration and dosing interval?

Administrative dose given rate of administration and dosing interval calculator uses Administered Dose = (Drug Rate of Administration*Dosing Interval)/(Bioavailability*Drug Purity) to calculate the Administered Dose, The Administrative dose given rate of administration and dosing interval formula is defined as the ratio of the rate of administered drug in particular time to the bioavailability of the pure drug. Administered Dose is denoted by D_a symbol.

How to calculate Administrative dose given rate of administration and dosing interval using this online calculator? To use this online calculator for Administrative dose given rate of administration and dosing interval, enter Drug Rate of Administration (V_a), Dosing Interval (Τ), Bioavailability (B) & Drug Purity (Q) and hit the calculate button. Here is how the Administrative dose given rate of administration and dosing interval calculation can be explained with given input values -> 2.3E+12 = (4.5E-05*44)/(12.5*69).

FAQ

What is Administrative dose given rate of administration and dosing interval?

The Administrative dose given rate of administration and dosing interval formula is defined as the ratio of the rate of administered drug in particular time to the bioavailability of the pure drug and is represented as D_a = (V_a*Τ)/(B*Q) or Administered Dose = (Drug Rate of Administration*Dosing Interval)/(Bioavailability*Drug Purity). Drug Rate of Administration is the amount of drug administered in a particular interval of time, The Dosing Interval is the time between drug dose administrations, The Bioavailability is the systemically available fraction of a drug & The Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present.

How to calculate Administrative dose given rate of administration and dosing interval?

The Administrative dose given rate of administration and dosing interval formula is defined as the ratio of the rate of administered drug in particular time to the bioavailability of the pure drug is calculated using Administered Dose = (Drug Rate of Administration*Dosing Interval)/(Bioavailability*Drug Purity). To calculate Administrative dose given rate of administration and dosing interval, you need Drug Rate of Administration (V_a), Dosing Interval (Τ), Bioavailability (B) & Drug Purity (Q). With our tool, you need to enter the respective value for Drug Rate of Administration, Dosing Interval, Bioavailability & Drug Purity and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Administered Dose?

In this formula, Administered Dose uses Drug Rate of Administration, Dosing Interval, Bioavailability & Drug Purity. We can use 2 other way(s) to calculate the same, which is/are as follows -

Administered Dose = Effective Dose/Bioavailability
Administered Dose = Effective Dose/(Drug Purity*Bioavailability)

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