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Administrative dose given effective dose and bioavailability Calculator

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✖The Effective Dose is a dose or concentration of a drug that produces a biological response.ⓘ Effective Dose [D_e]			+10% -10%
✖The Bioavailability is the systemically available fraction of a drug.ⓘ Bioavailability [B]			+10% -10%

✖Administered Dose is the amount of drug administered for a pharmacological response.ⓘ Administrative dose given effective dose and bioavailability [D_a]

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Administrative dose given effective dose and bioavailability Solution

STEP 0: Pre-Calculation Summary

Formula Used

Administered Dose = Effective Dose/Bioavailability
D_a = D_e/B
This formula uses 3 Variables

Variables Used

Administered Dose - (Measured in Kilogram) - Administered Dose is the amount of drug administered for a pharmacological response.
Effective Dose - (Measured in Kilogram) - The Effective Dose is a dose or concentration of a drug that produces a biological response.
Bioavailability - The Bioavailability is the systemically available fraction of a drug.

STEP 1: Convert Input(s) to Base Unit

Effective Dose: 5.5 Microgram --> 5.5E-09 Kilogram (Check conversion here)
Bioavailability: 12.5 --> No Conversion Required

STEP 2: Evaluate Formula

Substituting Input Values in Formula

D_a = D_e/B --> 5.5E-09/12.5

Evaluating ... ...

D_a = 4.4E-10

STEP 3: Convert Result to Output's Unit

4.4E-10 Kilogram -->0.44 Microgram (Check conversion here)

FINAL ANSWER

0.44 Microgram <-- Administered Dose

(Calculation completed in 00.004 seconds)

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Created by Prashant Singh

K J Somaiya College of science (K J Somaiya), Mumbai

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Administrative dose given effective dose and bioavailability Formula

LaTeX Go

Administered Dose = Effective Dose/Bioavailability
D_a = D_e/B

What is Pharmacokinetics?

Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.

How to Calculate Administrative dose given effective dose and bioavailability?

Administrative dose given effective dose and bioavailability calculator uses Administered Dose = Effective Dose/Bioavailability to calculate the Administered Dose, The Administrative dose given effective dose and bioavailability formula is defined as the ratio of the effective dose of the drug to the bioavailability of the fraction of drug. Administered Dose is denoted by D_a symbol.

How to calculate Administrative dose given effective dose and bioavailability using this online calculator? To use this online calculator for Administrative dose given effective dose and bioavailability, enter Effective Dose (D_e) & Bioavailability (B) and hit the calculate button. Here is how the Administrative dose given effective dose and bioavailability calculation can be explained with given input values -> 4.4E+8 = 5.5E-09/12.5.

FAQ

What is Administrative dose given effective dose and bioavailability?

The Administrative dose given effective dose and bioavailability formula is defined as the ratio of the effective dose of the drug to the bioavailability of the fraction of drug and is represented as D_a = D_e/B or Administered Dose = Effective Dose/Bioavailability. The Effective Dose is a dose or concentration of a drug that produces a biological response & The Bioavailability is the systemically available fraction of a drug.

How to calculate Administrative dose given effective dose and bioavailability?

The Administrative dose given effective dose and bioavailability formula is defined as the ratio of the effective dose of the drug to the bioavailability of the fraction of drug is calculated using Administered Dose = Effective Dose/Bioavailability. To calculate Administrative dose given effective dose and bioavailability, you need Effective Dose (D_e) & Bioavailability (B). With our tool, you need to enter the respective value for Effective Dose & Bioavailability and hit the calculate button. You can also select the units (if any) for Input(s) and the Output as well.

How many ways are there to calculate Administered Dose?

In this formula, Administered Dose uses Effective Dose & Bioavailability. We can use 2 other way(s) to calculate the same, which is/are as follows -

Administered Dose = Effective Dose/(Drug Purity*Bioavailability)
Administered Dose = (Drug Rate of Administration*Dosing Interval)/(Bioavailability*Drug Purity)

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